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Clinical Trials

1. Effect of Xuezhikang, an extract from red yeast Chinese rice, on coronary events in a Chinese population with previous myocardial infarction.

Author: Lu Z; Kou W; Du B; Wu Y; Zhao S; Brusco OA; Morgan JM; Capuzzi DM; Li S;
Institution: Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, Peoples Republic of China.
Journal: Am J Cardiol. 2008 Jun 15;101(12):1689-93. Epub 2008 Apr 11.
Abstract URL: Click here to view abstract

2. Rosuvastatin, pravastatin, and atorvastatin for the treatment of hypercholesterolaemia in HIV-infected patients receiving protease inhibitors.

Author: Calza L; Manfredi R; Colangeli V; Pocaterra D; Pavoni M; Chiodo F;
Institution: Department of Clinical and Experimental Medicine, Section of Infectious Diseases, Alma Mater Studiorum University of Bologna, S. Orsola Hospital, Bologna, Italy. leonardo.calza@unibo.it
Journal: Curr HIV Res. 2008 Nov;6(6):572-8.
Abstract URL: Click here to view abstract

3. Cholesterol lowering effect of a soy drink enriched with plant sterols in a French population with moderate hypercholesterolemia.

Author: Weidner C; Krempf M; Bard JM; Cazaubiel M; Bell D;
Institution: Cognis GmbH, Monheim, Germany. Christina.Weidner@cognis.com
Journal: Lipids Health Dis. 2008 Oct 6;7:35.
Abstract URL: Click here to view abstract

4. Ezetimibe 5 and 10 mg for lowering LDL-C: potential billion-dollar savings with improved tolerability.

Author: Baruch L; Gupta B; Lieberman-Blum SS; Agarwal S; Eng C;
Institution: James J Peters VA Medical Center, Bronx, NY 10468, USA. lawrence.baruch@va.gov
Journal: Am J Manag Care. 2008 Oct;14(10):637-41.
Abstract URL: Click here to view abstract

5. Ezetimibe alone reduces low-density lipoprotein cholesterol in HIV-infected patients receiving combination antiretroviral therapy.

Author: Wohl DA; Waters D; Simpson RJ Jr; Richard S; Schnell A; Napravnik S; Keys J; Eron JJ Jr; Hsue P;
Institution: University of North Carolina, Chapel Hill, NC 27599, USA. wohl@med.unc.edu
Journal: Clin Infect Dis. 2008 Oct 15;47(8):1105-8.
Abstract URL: Click here to view abstract

6. Simvastatin vs therapeutic lifestyle changes and supplements: randomized primary prevention trial.

Author: Becker DJ; Gordon RY; Morris PB; Yorko J; Gordon YJ; Li M; Iqbal N;
Institution: Division of Cardiology, Chestnut Hill Hospital, University of Pennsylvania Health System, Philadelphia, PA, USA. dbeckerchcardiology@hotmail.com
Journal: Mayo Clin Proc. 2008 Jul;83(7):758-64.
Abstract URL: Click here to view abstract

7. Simultaneous intake of beta-glucan and plant stanol esters affects lipid metabolism in slightly hypercholesterolemic subjects.

Author: Theuwissen E; Mensink RP;
Institution: Maastricht University, Department of Human Biology, 6200 MD Maastricht, The Netherlands.
Journal: J Nutr. 2007 Mar;137(3):583-8.
Abstract URL: Click here to view abstract

8. Efficacy and safety of rosuvastatin 40 mg alone or in combination with ezetimibe in patients at high risk of cardiovascular disease (results from the EXPLORER study).

Author: Ballantyne CM; Weiss R; Moccetti T; Vogt A; Eber B; Sosef F; Duffield E;
Institution: Methodist DeBakey Heart Center, Baylor College of Medicine, Houston, Texas, USA. cmb@bcm.tmc.edu
Journal: Am J Cardiol. 2007 Mar 1;99(5):673-80. Epub 2007 Jan 4.
Abstract URL: Click here to view abstract

9. The effect of strawberries in a cholesterol-lowering dietary portfolio.

Author: Jenkins DJ; Nguyen TH; Kendall CW; Faulkner DA; Bashyam B; Kim IJ; Ireland C; Patel D; Vidgen E; Josse AR; Sesso HD; Burton-Freeman B; Josse RG; Leiter LA; Singer W;
Institution: Clinical Nutrition & Risk Factor Modification Center, St Michael's Hospital, Toronto, Ontario, Canada.
Journal: Metabolism. 2008 Dec;57(12):1636-44.
Abstract URL: Click here to view abstract

10. Comparison of the safety and efficacy of a combination tablet of niacin extended release and simvastatin vs simvastatin monotherapy in patients with increased non-HDL cholesterol (from the SEACOAST I study).

Author: Ballantyne CM; Davidson MH; McKenney J; Keller LH; Bajorunas DR; Karas RH;
Institution: Baylor College of Medicine and Methodist DeBakey Heart and Vascular Center, Houston, Texas, USA. cmb@bcm.tmc.edu
Journal: Am J Cardiol. 2008 May 15;101(10):1428-36.
Abstract URL: Click here to view abstract

11. Reduction in the recurrence of stroke by eicosapentaenoic acid for hypercholesterolemic patients: subanalysis of the JELIS trial.

Author: Tanaka K; Ishikawa Y; Yokoyama M; Origasa H; Matsuzaki M; Saito Y; Matsuzawa Y; Sasaki J; Oikawa S; Hishida H; Itakura H; Kita T; Kitabatake A; Nakaya N; Sakata T; Shimada K; Shirato K;
Institution: Department of Neurology, Toyama University Hospital, 2630 Sugitani, Toyama, Toyama, 930-0194, Japan. kortaro@med.u-toyama.ac.jp
Journal: Stroke. 2008 Jul;39(7):2052-8. Epub 2008 May 1.
Abstract URL: Click here to view abstract

12. Simvastatin with or without ezetimibe in familial hypercholesterolemia.

Author: Kastelein JJ; Akdim F; Stroes ES; Zwinderman AH; Bots ML; Stalenhoef AF; Visseren FL; Sijbrands EJ; Trip MD; Stein EA; Gaudet D; Duivenvoorden R; Veltri EP; Marais AD; de Groot E;
Institution: Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands. j.j.kastelein@amc.uva.nl
Journal: N Engl J Med. 2008 Apr 3;358(14):1431-43. Epub 2008 Mar 30.
Abstract URL: Click here to view abstract

13. Progression of kidney disease in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin versus usual care: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Author: Rahman M; Baimbridge C; Davis BR; Barzilay J; Basile JN; Henriquez MA; Huml A; Kopyt N; Louis GT; Pressel SL; Rosendorff C; Sastrasinh S; Stanford C;
Institution: Case Western Reserve University, University Hospitals of Cleveland Case Medical Center, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA.
Journal: Am J Kidney Dis. 2008 Sep;52(3):412-24. Epub 2008 Aug 3.
Abstract URL: Click here to view abstract

14. Relationship between coronary events and serum cholesterol during 10 years of low-dose simvastatin therapy: long-term efficacy and safety in Japanese patients with hypercholesterolemia in the Japan Lipid Intervention Trial (J-LIT) Extension 10 Study, a prospective large-scale observational cohort study.

Author: Itakura H; Kita T; Mabuchi H; Matsuzaki M; Matsuzawa Y; Nakaya N; Oikawa S; Saito Y; Sasaki J; Shimamoto K;
Institution: Ibaraki Christian University, Hitachi, Japan.
Journal: Circ J. 2008 Aug;72(8):1218-24.
Abstract URL: Click here to view abstract

15. Combination of simvastatin with berberine improves the lipid-lowering efficacy.

Author: Kong WJ; Wei J; Zuo ZY; Wang YM; Song DQ; You XF; Zhao LX; Pan HN; Jiang JD;
Institution: Department of Pharmacology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Journal: Metabolism. 2008 Aug;57(8):1029-37.
Abstract URL: Click here to view abstract

16. A macadamia nut-rich diet reduces total and LDL-cholesterol in mildly hypercholesterolemic men and women.

Author: Griel AE; Cao Y; Bagshaw DD; Cifelli AM; Holub B; Kris-Etherton PM;
Institution: Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, 16802, USA.
Journal: J Nutr. 2008 Apr;138(4):761-7.
Abstract URL: Click here to view abstract

17. Efficacy of aerobic exercise on coronary heart disease risk factors.

Author: Kelley GA; Kelley KS;
Institution: Department of Community Medicine, School of Medicine, West Virginia University, Morgantown, WV 26506-9190, USA. gkelley@hsc.wvu.edu
Journal: Prev Cardiol. 2008 Spring;11(2):71-5.
Abstract URL: Click here to view abstract

18. Effect of lower targets for blood pressure and LDL cholesterol on atherosclerosis in diabetes: the SANDS randomized trial.

Author: Howard BV; Roman MJ; Devereux RB; Fleg JL; Galloway JM; Henderson JA; Howard WJ; Lee ET; Mete M; Poolaw B; Ratner RE; Russell M; Silverman A; Stylianou M; Umans JG; Wang W; Weir MR; Weissman NJ; Wilson C; Yeh F; Zhu J; Howard BV; Roman MJ; Devereux RB; Fleg JL; Galloway JM; Henderson JA; Howard WJ; Lee ET; Mete M; Poolaw B; Ratner RE; Russell M; Silverman A; Stylianou M; Umans JG; Wang W; Weir MR; Weissman NJ; Wilson C; Yeh F; Zhu J;
Institution: MedStar Research Institute, 6495 New Hampshire Ave, Suite 201, Hyattsville, MD 20783, USA. barbara.v.howard@medstar.net
Journal: JAMA. 2008 Apr 9;299(14):1678-89.
Abstract URL: Click here to view abstract

19. Effect of citrus flavonoids and tocotrienols on serum cholesterol levels in hypercholesterolemic subjects.

Author: Roza JM; Xian-Liu Z; Guthrie N;
Institution: SourceOne Global Partners, Chicago, Illinois, USA.
Journal: Altern Ther Health Med. 2007 Nov-Dec;13(6):44-8.
Abstract URL: Click here to view abstract

20. Olive oil containing olive oil fatty acid esters of plant sterols and dietary diacylglycerol reduces low-density lipoprotein cholesterol and decreases the tendency for peroxidation in hypercholesterolaemic subjects.

Author: Chan YM; Demonty I; Pelled D; Jones PJ;
Institution: The School of Dietetics and Human Nutrition, McGill University, Macdonald Campus, 21,111 Lakeshore Road, Sainte-Anne-de-Bellevue, Quebec, Canada H9X 3V9.
Journal: Br J Nutr. 2007 Sep;98(3):563-70. Epub 2007 Jun 11.
Abstract URL: Click here to view abstract

21. Comparison of effects of ezetimibe/simvastatin versus simvastatin versus atorvastatin in reducing C-reactive protein and low-density lipoprotein cholesterol levels.

Author: Pearson T; Ballantyne C; Sisk C; Shah A; Veltri E; Maccubbin D;
Institution: University of Rochester School of Medicine and Dentistry, Rochester, New York, USA. thomas_pearson@urmc.rochester.edu
Journal: Am J Cardiol. 2007 Jun 15;99(12):1706-1713. Epub 2007 May 2.
Abstract URL: Click here to view abstract

22. Efficacy of Monascus purpureus Went rice on lowering lipid ratios in hypercholesterolemic patients.

Author: Huang CF; Li TC; Lin CC; Liu CS; Shih HC; Lai MM;
Institution: Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan, Republic of China.
Journal: Eur J Cardiovasc Prev Rehabil. 2007 Jun;14(3):438-40.
Abstract URL: Click here to view abstract

23. Effects of vitamin E on cholesterol levels of hypercholesterolemic patients receiving statins.

Author: Leonard SW; Joss JD; Mustacich DJ; Blatt DH; Lee YS; Traber MG;
Institution: Linus Pauling Institute, Oregon State University, 571 Weniger Hall, Corvallis, OR 97331, USA.
Journal: Am J Health Syst Pharm. 2007 Nov 1;64(21):2257-66.
Abstract URL: Click here to view abstract

24. Suboptimal control of glycemia, blood pressure, and LDL cholesterol in overweight adults with diabetes: the Look AHEAD Study.

Author: Bertoni AG; Clark JM; Feeney P; Yanovski SZ; Bantle J; Montgomery B; Safford MM; Herman WH; Haffner S;
Institution: Division of Public Health Sciences, Department of Epidemiology and Prevention, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA. abertoni@wfubmc.edu
Journal: J Diabetes Complications. 2008 Jan-Feb;22(1):1-9.
Abstract URL: Click here to view abstract

25. Improved attainment of blood pressure and cholesterol goals using single-pill amlodipine/atorvastatin in African Americans: the CAPABLE trial.

Author: Flack JM; Victor R; Watson K; Ferdinand KC; Saunders E; Tarasenko L; Jamieson MJ; Shi H; Bruschi P;
Institution: Department of Medicine, Wayne State University, Detroit, MI 48201, USA. jflack@med.wayne.edu
Journal: Mayo Clin Proc. 2008 Jan;83(1):35-45.
Abstract URL: Click here to view abstract

26. A multicentre, open study to assess the effect of individualizing starting doses of atorvastatin according to baseline LDL-C levels on achieving cholesterol targets: the Achieve Cholesterol Targets Fast with Atorvastatin Stratified Titration (ACTFAST-2) study.

Author: Farsang C; Athyros V; Gaw A;
Institution: First Department of Medicine, Semmelweis University, Budapest, Hungary. farsang@bell.sote.hu <farsang@bell.sote.hu>
Journal: Curr Med Res Opin. 2007 Aug;23(8):1945-56.
Abstract URL: Click here to view abstract

27. Beneficial effects of periodontal treatment on metabolic control of hypercholesterolemia.

Author: Oz SG; Fentoglu O; Kilicarslan A; Guven GS; Tanrtover MD; Aykac Y; Sozen T;
Institution: Hacettepe University Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey. irem8886@yahoo.com
Journal: South Med J. 2007 Jul;100(7):686-91.
Abstract URL: Click here to view abstract

28. Effect of plant sterols and exercise training on cholesterol absorption and synthesis in previously sedentary hypercholesterolemic subjects.

Author: Varady KA; Houweling AH; Jones PJ;
Institution: School of Dietetics and Human Nutrition, Faculty of Agricultural and Environmental Sciences, McGill University, Montreal, Quebec, Canada.
Journal: Transl Res. 2007 Jan;149(1):22-30.
Abstract URL: Click here to view abstract

29. Improved coronary vasodilatatory capacity by H.E.L.P. apheresis: comparing initial and chronic treatment.

Author: Mellwig KP; van Buuren F; Schmidt HK; Wielepp P; Burchert W; Horstkotte D;
Institution: Department of Cardiology, Nuclear Medicine and Molecular Imaging, Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany. akohlstaedt@hdz-nrw.de
Journal: Ther Apher Dial. 2006 Dec;10(6):510-7.
Abstract URL: Click here to view abstract

30. Cholesterol-lowering ability of a phytostanol softgel supplement in adults with mild to moderate hypercholesterolemia.

Author: Woodgate D; Chan CH; Conquer JA;
Institution: Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario N1G 5B6, Canada.
Journal: Lipids. 2006 Feb;41(2):127-32.
Abstract URL: Click here to view abstract

31. Combination of chromium and biotin improves coronary risk factors in hypercholesterolemic type 2 diabetes mellitus: a placebo-controlled, double-blind randomized clinical trial.

Author: Albarracin C; Fuqua B; Geohas J; Juturu V; Finch MR; Komorowski JR;
Institution: Alpha Therapy Center, Corpus Christi, TX, USA.
Journal: J Cardiometab Syndr. 2007 Spring;2(2):91-7.
Abstract URL: Click here to view abstract

32. A multi-centre, randomised, double-blind 14-week extension study examining the long-term safety and efficacy profile of the ezetimibe/simvastatin combination tablet.

Author: Ose L; Johnson-Levonas A; Reyes R; Lin J; Shah A; Tribble D; Musliner T;
Institution: Lipid Clinic, Rikshospitalet, Oslo, Norway. liv.ose@rikshospitalet.no
Journal: Int J Clin Pract. 2007 Sep;61(9):1469-80. Epub 2007 Jul 26.
Abstract URL: Click here to view abstract

33. Reduction in estimated risk for coronary artery disease after use of ezetimibe with a statin.

Author: Sampalis JS; Bissonnette S; Habib R; Boukas S;
Institution: Department of Surgery and Epidemiology, McGill University, Montreal, Quebec, Canada. jsampalis@jssresearch.com
Journal: Ann Pharmacother. 2007 Sep;41(9):1345-51. Epub 2007 Jul 31.
Abstract URL: Click here to view abstract

34. Intake of phenol-rich virgin olive oil improves the postprandial prothrombotic profile in hypercholesterolemic patients.

Author: Ruano J; Lopez-Miranda J; de la Torre R; Delgado-Lista J; Fernandez J; Caballero J; Covas MI; Jimenez Y; Perez-Martinez P; Marin C; Fuentes F; Perez-Jimenez F;
Institution: Lipids and Atherosclerosis Research Unit, Reina Sofia University Hospital, University of Cordoba, Ciber Fisiopatologia Obesidad y Nutricion, Instituto de Salud Carlos III, Spain.
Journal: Am J Clin Nutr. 2007 Aug;86(2):341-6.
Abstract URL: Click here to view abstract

35. Contemporary diagnosis and management of hypercholesterolemia in elderly acute myocardial infarction patients: a population-based study.

Author: Berger AK; Duval SJ; Armstrong C; Jacobs DR Jr; Luepker RV;
Institution: Section of Cardiovascular Medicine, Department of Medicine, and the Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454, USA. berger1217@aol.com
Journal: Am J Geriatr Cardiol. 2007 Jan-Feb;16(1):15-23.
Abstract URL: Click here to view abstract

36. Effectiveness of ezetimibe added to ongoing statin therapy in modifying lipid profiles and low-density lipoprotein cholesterol goal attainment in patients of different races and ethnicities: a substudy of the Ezetimibe add-on to statin for effectiveness trial.

Author: Pearson TA; Denke MA; McBride PE; Battisti WP; Gazzara RA; Brady WE; Palmisano J;
Institution: Department of Community & Preventive Medicine, University of Rochester School of Medicine and Dentistry, NY 14642, USA.
Journal: Mayo Clin Proc. 2006 Sep;81(9):1177-85.
Abstract URL: Click here to view abstract

37. Lipid-lowering effects of colesevelam HCl in combination with ezetimibe.

Author: Bays H; Rhyne J; Abby S; Lai YL; Jones M;
Institution: Louisville Metabolic and Atherosclerosis Research Center Inc., Louisville, KY 40213, USA. hbaysmd@aol.com
Journal: Curr Med Res Opin. 2006 Nov;22(11):2191-200.
Abstract URL: Click here to view abstract

38. Cocoa flavanol-enriched snack bars containing phytosterols effectively lower total and low-density lipoprotein cholesterol levels.

Author: Polagruto JA; Wang-Polagruto JF; Braun MM; Lee L; Kwik-Uribe C; Keen CL;
Institution: Department of Nutrition, University of California, Davis, USA.
Journal: J Am Diet Assoc. 2006 Nov;106(11):1804-13.
Abstract URL: Click here to view abstract

39. Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels.

Author: Davidson MH; McKenney JM; Shear CL; Revkin JH;
Institution: Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA. michaeldavidson@radiantresearch.com
Journal: J Am Coll Cardiol. 2006 Nov 7;48(9):1774-81.
Abstract URL: Click here to view abstract

40. Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels on a background of atorvastatin.

Author: McKenney JM; Davidson MH; Shear CL; Revkin JH;
Institution: Virginia Commonwealth University, Richmond, Virginia, USA. jmckenney@ncrinc.net
Journal: J Am Coll Cardiol. 2006 Nov 7;48(9):1782-90.
Abstract URL: Click here to view abstract

41. A randomized clinical trial testing treatment preference and two dietary options in behavioral weight management: preliminary results of the impact of diet at 6 months--PREFER study.

Author: Burke LE; Styn MA; Steenkiste AR; Music E; Warziski M; Choo J;
Institution: School of Nursing, University of Pittsburgh, 3500 Victoria Street, 415 Victoria Building, Pittsburgh, PA 15261, USA. lbu100@pitt.edu
Journal: Obesity (Silver Spring). 2006 Nov;14(11):2007-17.
Abstract URL: Click here to view abstract

42. Comparative lipid-lowering effects of policosanol and atorvastatin: a randomized, parallel, double-blind, placebo-controlled trial.

Author: Cubeddu LX; Cubeddu RJ; Heimowitz T; Restrepo B; Lamas GA; Weinberg GB;
Institution: Division of Cardiology and Department of Internal Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140, USA.
Journal: Am Heart J. 2006 Nov;152(5):982.e1-5.
Abstract URL: Click here to view abstract

43. A combination therapy including psyllium and plant sterols lowers LDL cholesterol by modifying lipoprotein metabolism in hypercholesterolemic individuals.

Author: Shrestha S; Volek JS; Udani J; Wood RJ; Greene CM; Aggarwal D; Contois JH; Kavoussi B; Fernandez ML;
Institution: Liposcience Inc., Raleigh, NC 27616.
Journal: J Nutr. 2006 Oct;136(10):2492-7.
Abstract URL: Click here to view abstract

44. Efficacy and safety of rosuvastatin every other day compared with once daily in patients with hypercholesterolemia.

Author: Wongwiwatthananukit S; Sansanayudh N; Dhummauppakorn R; Kitiyadisai C;
Institution: Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand. supakit.w@chula.ac.th
Journal: Ann Pharmacother. 2006 Nov;40(11):1917-23. Epub 2006 Sep 26.
Abstract URL: Click here to view abstract

45. Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): a prospective randomised controlled trial.

Author: Nakamura H; Arakawa K; Itakura H; Kitabatake A; Goto Y; Toyota T; Nakaya N; Nishimoto S; Muranaka M; Yamamoto A; Mizuno K; Ohashi Y;
Institution: Mitsukoshi Health and Welfare Foundation, Tokyo, Japan. nakamura@mhwf.or.jp
Journal: Lancet. 2006 Sep 30;368(9542):1155-63.
Abstract URL: Click here to view abstract

46. Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients.

Author: Catapano AL; Davidson MH; Ballantyne CM; Brady WE; Gazzara RA; Tomassini JE; Tershakovec AM;
Institution: University of Milan, Milan, Italy. Alberico.Catapano@unimi.it
Journal: Curr Med Res Opin. 2006 Oct;22(10):2041-53.
Abstract URL: Click here to view abstract

47. Efficacy and tolerability of ezetimibe 10 mg/day coadministered with statins in patients with primary hypercholesterolemia who do not achieve target LDL-C while on statin monotherapy: A Canadian, multicentre, prospective study--the Ezetrol Add-On Study.

Author: Bissonnette S; Habib R; Sampalis F; Boukas S; Sampalis JS;
Institution: Merck Frosst/Schering Pharmaceuticals, Kirkland, Canada.
Journal: Can J Cardiol. 2006 Oct;22(12):1035-44.
Abstract URL: Click here to view abstract

48. Fish-oil esters of plant sterols improve the lipid profile of dyslipidemic subjects more than do fish-oil or sunflower oil esters of plant sterols.

Author: Demonty I; Chan YM; Pelled D; Jones PJ;
Institution: School of Dietetics and Human Nutrition, McGill University, Sainte-Anne-de-Bellevue, Canada.
Journal: Am J Clin Nutr. 2006 Dec;84(6):1534-42.
Abstract URL: Click here to view abstract

49. Policosanol is ineffective in the treatment of hypercholesterolemia: a randomized controlled trial.

Author: Dulin MF; Hatcher LF; Sasser HC; Barringer TA;
Institution: Carolinas Medical Center Department of Family Medicine, Charlotte, NC, USA. michael.dulin@carolinashealthcare.org
Journal: Am J Clin Nutr. 2006 Dec;84(6):1543-8.
Abstract URL: Click here to view abstract

50. Dual cholesterol inhibition with ezetimibe/simvastatin in pre-treated hypercholesterolaemic patients with coronary heart disease or diabetes mellitus: prospective observational cohort studies in clinical practice.

Author: Hildemann SK; Barho C; Karmann B; Darius H; Bestehorn K;
Institution: Essex pharma, Medical Department, Munich, Germany. steven.hildemann@essex.de
Journal: Curr Med Res Opin. 2007 Apr;23(4):713-9.
Abstract URL: Click here to view abstract

51. Efficacy and safety of ezetimibe co-administered with atorvastatin in untreated patients with primary hypercholesterolaemia and coronary heart disease.

Author: Blagden MD; Chipperfield R;
Institution: Avondale Surgery, Chesterfield, UK. admin@avondaleresearch.co.uk <admin@avondaleresearch.co.uk>
Journal: Curr Med Res Opin. 2007 Apr;23(4):767-75.
Abstract URL: Click here to view abstract

52. Effect of soy protein from differently processed products on cardiovascular disease risk factors and vascular endothelial function in hypercholesterolemic subjects.

Author: Matthan NR; Jalbert SM; Ausman LM; Kuvin JT; Karas RH; Lichtenstein AH;
Institution: Cardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA. nirupa.matthan@tufts.edu
Journal: Am J Clin Nutr. 2007 Apr;85(4):960-6.
Abstract URL: Click here to view abstract

53. Oat-derived beta-glucan significantly improves HDLC and diminishes LDLC and non-HDL cholesterol in overweight individuals with mild hypercholesterolemia.

Author: Reyna-Villasmil N; Bermudez-Pirela V; Mengual-Moreno E; Arias N; Cano-Ponce C; Leal-Gonzalez E; Souki A; Inglett GE; Israili ZH; Hernandez-Hernandez R; Valasco M; Arraiz N;
Institution: Center for Metabolic and Endocrine Research, The University of Zulia, Maracaibo, Venezuela. nadiareyna@hotmail.com
Journal: Am J Ther. 2007 Mar-Apr;14(2):203-12.
Abstract URL: Click here to view abstract

54. Concentrated oat beta-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial.

Author: Queenan KM; Stewart ML; Smith KN; Thomas W; Fulcher RG; Slavin JL;
Institution: Department of Food Science and Nutrition, University of Minnesota, St. Paul, MN, USA.
Journal: Nutr J. 2007 Mar 26;6:6.
Abstract URL: Click here to view abstract

55. Effects of a potent and selective PPAR-alpha agonist in patients with atherogenic dyslipidemia or hypercholesterolemia: two randomized controlled trials.

Author: Nissen SE; Nicholls SJ; Wolski K; Howey DC; McErlean E; Wang MD; Gomez EV; Russo JM;
Institution: Department of Cardiovascular Medicine, Cleveland Clinic Lerner School of Medicine, Cleveland, Ohio 44195, USA. nissens@ccf.org
Journal: JAMA. 2007 Mar 28;297(12):1362-73. Epub 2007 Mar 25.
Abstract URL: Click here to view abstract

56. Effect of raw garlic vs commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia: a randomized clinical trial.

Author: Gardner CD; Lawson LD; Block E; Chatterjee LM; Kiazand A; Balise RR; Kraemer HC;
Institution: Stanford Prevention Research Center and Department of Medicine, Stanford University Medical School, Stanford, Calif 94305, USA. cgardner@stanford.edu
Journal: Arch Intern Med. 2007 Feb 26;167(4):346-53.
Abstract URL: Click here to view abstract

57. Do trans fatty acids from industrially produced sources and from natural sources have the same effect on cardiovascular disease risk factors in healthy subjects? Results of the trans Fatty Acids Collaboration (TRANSFACT) study.

Author: Chardigny JM; Destaillats F; Malpuech-Brugere C; Moulin J; Bauman DE; Lock AL; Barbano DM; Mensink RP; Bezelgues JB; Chaumont P; Combe N; Cristiani I; Joffre F; German JB; Dionisi F; Boirie Y; Sebedio JL;
Institution: Institut National de Recherche Agronomique and Food Science, UMR1019, Clermont-Ferrand, France.
Journal: Am J Clin Nutr. 2008 Mar;87(3):558-66.
Abstract URL: Click here to view abstract

58. Dose-dependent cholesterol-lowering effect of a mayonnaise-type product with a main component of diacylglycerol-containing plant sterol esters.

Author: Saito S; Takeshita M; Tomonobu K; Kudo N; Shiiba D; Hase T; Tokimitsu I; Yasukawa T;
Institution: Health Care Products Research Laboratories No. 1, Kao Corporation, Tokyo, Japan.
Journal: Nutrition. 2006 Feb;22(2):174-8.
Abstract URL: Click here to view abstract

59. Relation between on-treatment increments in serum high-density lipoprotein cholesterol levels and cardiac mortality in patients with coronary heart disease (from the Bezafibrate Infarction Prevention trial).

Author: Goldenberg I; Goldbourt U; Boyko V; Behar S; Reicher-Reiss H;
Institution: Heart Institute, Sheba Medical Center, Tel Hashomer, Israel.
Journal: Am J Cardiol. 2006 Feb 15;97(4):466-71. Epub 2005 Dec 22.
Abstract URL: Click here to view abstract

60. Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: a randomized, double blind placebo controlled trial.

Author: Bundy R; Walker AF; Middleton RW; Wallis C; Simpson HC;
Institution: Hugh Sinclair Unit of Human Nutrition, School of Chemistry, Food Biosciences & Pharmacy, The University of Reading, Reading, UK.
Journal: Phytomedicine. 2008 Sep;15(9):668-75.
Abstract URL: Click here to view abstract

61. Beneficial effects of aggressive low-density lipoprotein cholesterol lowering in women with stable coronary heart disease in the Treating to New Targets (TNT) study.

Author: Wenger NK; Lewis SJ; Welty FK; Herrington DM; Bittner V;
Institution: Emory University School of Medicine, 49 Jesse Hill Jr Drive, SE Atlanta, GA 30303, USA. nwenger@emory.edu
Journal: Heart. 2008 Apr;94(4):434-9. Epub 2007 Dec 10.
Abstract URL: Click here to view abstract

62. Dietary flaxseed lignan extract lowers plasma cholesterol and glucose concentrations in hypercholesterolaemic subjects.

Author: Zhang W; Wang X; Liu Y; Tian H; Flickinger B; Empie MW; Sun SZ;
Institution: Tumor Hospital and Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Journal: Br J Nutr. 2008 Jun;99(6):1301-9. Epub 2007 Dec 6.
Abstract URL: Click here to view abstract

63. Treatment potential for cholesterol management in patients with coronary heart disease in 15 European countries: findings from the EUROASPIRE II survey.

Author: Kotseva K; Stagmo M; De Bacquer D; De Backer G; Wood D;
Institution: Cardiovascular Medicine, National Heart and Lung Institute, Imperial College London, Charing Cross Hospital 5th Floor, Laboratory Block, Fulham Palace Road, London W6 8RF, United Kingdom. k.kotseva@imperial.ac.uk
Journal: Atherosclerosis. 2008 Apr;197(2):710-7. Epub 2007 Sep 4.
Abstract URL: Click here to view abstract

64. Comparison of rosuvastatin versus atorvastatin in Hispanic-Americans with hypercholesterolemia (from the STARSHIP trial).

Author: Lloret R; Ycas J; Stein M; Haffner S;
Institution: Cardiovascular Center of South Florida, Miami, Florida, USA.
Journal: Am J Cardiol. 2006 Sep 15;98(6):768-73. Epub 2006 Jul 28.
Abstract URL: Click here to view abstract

65. Intake of a single morning dose of standard and novel plant sterol preparations for 4 weeks does not dramatically affect plasma lipid concentrations in humans.

Author: AbuMweis SS; Vanstone CA; Ebine N; Kassis A; Ausman LM; Jones PJ; Lichtenstein AH;
Institution: School of Dietetics and Human Nutrition, McGill University, Montreal, Quebec, Canada.
Journal: J Nutr. 2006 Apr;136(4):1012-6.
Abstract URL: Click here to view abstract

66. Achieving LDL cholesterol, non-HDL cholesterol, and apolipoprotein B target levels in high-risk patients: Measuring Effective Reductions in Cholesterol Using Rosuvastatin therapY (MERCURY) II.

Author: Ballantyne CM; Bertolami M; Hernandez Garcia HR; Nul D; Stein EA; Theroux P; Weiss R; Cain VA; Raichlen JS;
Institution: Methodist DeBakey Heart Center, Baylor College of Medicine, Houston, TX, USA. cmb@bcm.tmc.edu
Journal: Am Heart J. 2006 May;151(5):975.e1-9.
Abstract URL: Click here to view abstract

67. Efficacy and safety of coadministration of ezetimibe and simvastatin in African-American patients with primary hypercholesterolemia.

Author: Rodney RA; Sugimoto D; Wagman B; Zieve F; Kerzner B; Strony J; Yang B; Suresh R; Veltri E;
Institution: Schering Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033-1300, USA. roxanne.rodney@spcorp.com
Journal: J Natl Med Assoc. 2006 May;98(5):772-8.
Abstract URL: Click here to view abstract

68. Whole-grain diets reduce blood pressure in mildly hypercholesterolemic men and women.

Author: Behall KM; Scholfield DJ; Hallfrisch J;
Institution: Diet and Human Performance Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD 20705-2350, USA. behallk@ba.ars.usda.gov
Journal: J Am Diet Assoc. 2006 Sep;106(9):1445-9.
Abstract URL: Click here to view abstract