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New Developments in Chronic Pancreatitis
- Investigation continues into the genetic mutations that are present with different types of pancreatitis and what factors determine whether a person will contract the condition or not. For example, researchers are trying to understand why some alcoholic abusers develop pancreatitis and others do not.
- Research continues regarding the relationship between acute and chronic pancreatitis. Some studies seem to indicate that they comprise an extension of one disease as opposed to separate conditions.
- Endoscopic procedures to reduce pressure buildup in the ducts leading out of the pancreas and relieve pain continue to improve in their efficacy and safety.
- Laparoscopic techniques are used on a limited basis for treatment of chronic pancreatitis but research continues to investigate ways to broaden their application.
- Improvements in radiological imaging techniques are making the need for more invasive diagnostic procedures less necessary.
- Chemical substances released from cells called cytokines are under investigation. These proinflammatory chemicals may be responsible for the flare up of acute pancreatitis. Antibodies to inhibit or neutralize their effects are being investigated as new treatments for pancreatitis.
- Spinal cord stimulation shows promise as an alternative treatment for pain associated with CP. An electrode is implanted in the spine that delivers electrical impulses that block the transmission of the pain signal. A small study of five patients with CP reported that all patients reported a 50-80% reduction in narcotics use.
- Information regarding ongoing clinical studies in your area can be obtained at the Clinical Trials Listing Service at http://www.centerwatch.com.
