Diagnosis of Chronic Myelogenous Leukemia

Signs and Symptoms of Chronic Myelogenous Leukemia

Approximately 40% to 50% of patients in the chronic phase of chronic myelogenous leukemia (CML) have no clinical symptoms (asymptomatic) and the disease is usually discovered by a routine blood test or physical examination. Signs and symptoms of chronic myelogenous leukemia may include:

  • Generalized feeling of fatigue that won't go away
  • Fever
  • Night sweats
  • Upper abdominal pain or an abdominal mass
  • Enlargement of the spleen (splenomegaly) - occurs in about 50% of cases
  • Enlargement of the liver (hepatomegaly) - occurs in about 15% of cases
  • Pale complexion due to anemia