Sunday, October 12, 2008 - 5:01AM EST

Drug Therapy

1. Berbamine: a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity.

Author
Xu R; Dong Q; Yu Y; Zhao X; Gan X; Wu D; Lu Q; Xu X; Yu XF;
Institution
Department of Hematology, Second Affiliated Hospital, Hangzhou, Zhejiang Province 310009,China. zrxyk10@zju.edu.cn
Journal
Leuk Res. 2006 Jan;30(1):17-23. Epub 2005 Jul 14.
Abstract URL
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2. Sudden blastic transformation in patients with chronic myeloid leukemia treated with imatinib mesylate.

Author
Jabbour E; Kantarjian H; O'Brien S; Rios MB; Abruzzo L; Verstovsek S; Garcia-Manero G; Cortes J;
Institution
Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
Journal
Blood. 2006 Jan 15;107(2):480-2. Epub 2005 Sep 29.
Abstract URL
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3. High-dose imatinib mesylate combined with vincristine and dexamethasone (DIV regimen) as induction therapy in patients with resistant Philadelphia-positive acute lymphoblastic leukemia and lymphoid blast crisis of chronic myeloid leukemia.

Author
Rea D; Legros L; Raffoux E; Thomas X; Turlure P; Maury S; Dupriez B; Pigneux A; Choufi B; Reman O; Stephane D; Royer B; Vigier M; Ojeda-Uribe M; Recher C; Dombret H; Huguet F; Rousselot P;
Institution
Service d'Hematologie Clinique, Hopital Saint-Louis, Paris, France.
Journal
Leukemia. 2006 Mar;20(3):400-3.
Abstract URL
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4. Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia.

Author
Weisberg E; Manley PW; Cowan-Jacob SW; Hochhaus A; Griffin JD;
Institution
Dana Farber Cancer Institute, Mayer 540, 44 Binney Street, Boston, MA 02115, USA.
Journal
Nat Rev Cancer. 2007 May;7(5):345-56.
Abstract URL
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5. Long-term outcome of complete cytogenetic responders after imatinib 400 mg in late chronic phase, philadelphia-positive chronic myeloid leukemia: the GIMEMA Working Party on CML.

Author
Palandri F; Iacobucci I; Martinelli G; Amabile M; Poerio A; Testoni N; Soverini S; Castagnetti F; De Vivo A; Breccia M; Specchia G; Abruzzese E; Martino B; Cilloni D; Saglio G; Pane F; Liberati AM; Rosti G; Baccarani M;
Institution
Department of Hematology/Oncology L. and A. Seragnoli S. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy. francesca.palandri@libero.it
Journal
J Clin Oncol. 2008 Jan 1;26(1):106-11.
Abstract URL
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6. Effects of the mean daily doses of imatinib during the first year on survival of patients with chronic myeloid leukemia in Japan: a study of the Hokkaido Hematology Study Group.

Author
Sugita J; Tanaka J; Kurosawa M; Fukuhara T; Hashino S; Torimoto E; Koizumi K; Masauji N; Nishimura S; Koda K; Imamura M; Kasai M;
Institution
Department of Hematology and Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Journal
Eur J Haematol. 2008 Feb;80(2):160-3. Epub 2007 Nov 17.
Abstract URL
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7. FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia.

Author
Neviani P; Santhanam R; Oaks JJ; Eiring AM; Notari M; Blaser BW; Liu S; Trotta R; Muthusamy N; Gambacorti-Passerini C; Druker BJ; Cortes J; Marcucci G; Chen CS; Verrills NM; Roy DC; Caligiuri MA; Bloomfield CD; Byrd JC; Perrotti D;
Institution
Human Cancer Genetics Program, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, USA.
Journal
J Clin Invest. 2007 Sep;117(9):2408-21.
Abstract URL
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8. Drug evaluation: Nilotinib - a novel Bcr-Abl tyrosine kinase inhibitor for the treatment of chronic myelocytic leukemia and beyond.

Author
Jabbour E; Cortes J; Giles F; O'Brien S; Kantarijan H;
Institution
Department of Leukemia, Unit 428, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
Journal
IDrugs. 2007 Jul;10(7):468-79.
Abstract URL
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9. Dasatinib.

Author
Shah NP;
Institution
Division of Hematology/Oncology, UCSF School of Medicine, San Francisco, California 94143, USA. nshah@medicine.ucsf.edu
Journal
Drugs Today (Barc). 2007 Jan;43(1):5-12.
Abstract URL
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10. A pilot study of imatinib, low-dose cytarabine and idarubicin for patients with chronic myeloid leukemia in myeloid blast phase.

Author
Quintas-Cardama A; Kantarjian H; Garcia-Manero G; O'Brien S; Faderl S; Ravandi F; Giles F; Thomas D; Wierda W; Cortes J;
Institution
Department of Leukemia, The University of Texas M. D. Anderson Cancer Center. Houston, TX 77030, USA.
Journal
Leuk Lymphoma. 2007 Feb;48(2):283-9.
Abstract URL
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