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The prognosis for patients with Graves' disease (GD) is generally very positive with appropriate treatment, though many patients will have to remain on life-long thyroid replacement therapy. If left untreated, however, Graves' disease can lead to serious and potentially life-threatening complications. Most symptoms associated with Graves' disease respond well to various forms of treatment. Although many patients experience periods of remission (cessation of symptoms) for many years following treatment, it is important to remember that Graves' disease is a chronic condition which can be managed with various treatments but, as yet, cannot be cured. Patients must typically be monitored for the development of hypothyroidism or for recurrence of Graves' disease, either of which requires additional treatment. Patients who have undergone a complete thyroidectomy must remain on life-long thyroid replacement therapy.

Patients with Graves' disease should remain alert for complications that could develop, including:

• Development of Graves' ophthalmopathy
• Atrial fibrillation
• Osteoporosis
• Thyroid storm
• Skin symptoms
• Symptoms of inadequate levels of thyroid hormones, including weight gain, fatigue, elevated cholesterol, or depression