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Clinical Trials

1. Long-term efficacy of insulin glargine therapy with an educational programme in type 1 diabetes patients in clinical practice.

Author: Schreiber SA; Russmann A;
Institution: Diabetes Practice, Quickborn, Germany. stephan.schreiber@diabetes-hamburg.de
Journal: Curr Med Res Opin. 2007 Dec;23(12):3131-6.
Abstract URL: Click here to view abstract

2. Continuous subcutaneous insulin infusion benefits quality of life in preschool-age children with type 1 diabetes mellitus.

Author: Opipari-Arrigan L; Fredericks EM; Burkhart N; Dale L; Hodge M; Foster C;
Institution: Division of Child Behavioral Health, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Journal: Pediatr Diabetes. 2007 Dec;8(6):377-83.
Abstract URL: Click here to view abstract

3. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis.

Author: Kearney PM; Blackwell L; Collins R; Keech A; Simes J; Peto R; Armitage J; Baigent C; Kearney PM; Blackwell L; Collins R; Keech A; Simes J; Peto R; Armitage J; Baigent C; Kearney PM; Blackwell L; Collins R; Keech A; Simes J; Peto R; Armitage J; Baigent C;
Institution
Journal: Lancet. 2008 Jan 12;371(9607):117-25.
Abstract URL: Click here to view abstract

4. Trends in prevalence and outcomes of pregnancy in women with pre-existing type I and type II diabetes.

Author: Bell R; Bailey K; Cresswell T; Hawthorne G; Critchley J; Lewis-Barned N;
Institution: Institute of Health and Society, Newcastle University, Newcastle-upon-Tyne, UK. ruth.bell@ncl.ac.uk
Journal: BJOG. 2008 Mar;115(4):445-52.
Abstract URL: Click here to view abstract

5. A randomized, controlled trial comparing twice-a-day insulin glargine mixed with rapid-acting insulin analogs versus standard neutral protamine Hagedorn (NPH) therapy in newly diagnosed type 1 diabetes.

Author: Hassan K; Rodriguez LM; Johnson SE; Tadlock S; Heptulla RA;
Institution: Department of Pediatric Endocrinology and Metabolism, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Journal: Pediatrics. 2008 Mar;121(3):e466-72. Epub 2008 Feb 25.
Abstract URL: Click here to view abstract

6. Early nutrition and risk of Type 1 diabetes mellitus--a nationwide case-control study in preschool children.

Author: Rosenbauer J; Herzig P; Kaiser P; Giani G;
Institution: German Diabetes Clinic, German Diabetes Centre, Leibniz Centre at the Heinrich-Heine-University Dusseldorf, Auf'm Hennekamp 65, 40221 Dusseldorf, Germany. Joachim.Rosenbauer@ddz.uni-duesseldorf.de
Journal: Exp Clin Endocrinol Diabetes. 2007 Sep;115(8):502-8.
Abstract URL: Click here to view abstract

7. Continuous glucose monitoring in children with type 1 diabetes.

Author: Buckingham B; Beck RW; Tamborlane WV; Xing D; Kollman C; Fiallo-Scharer R; Mauras N; Ruedy KJ; Tansey M; Weinzimer SA; Wysocki T;
Institution
Journal: J Pediatr. 2007 Oct;151(4):388-93, 393.e1-2. Epub 2007 Aug 24.
Abstract URL: Click here to view abstract

8. Becoming pregnant: exploring the perspectives of women living with diabetes.

Author: Griffiths F; Lowe P; Boardman F; Ayre C; Gadsby R;
Institution: Health Sciences Research Institute, Warwick Mediical School, University of Warwick, Coventry, CV4 7Al. f.e.griffiths@warwick.ac.uk
Journal: Br J Gen Pract. 2008 Mar;58(548):184-90.
Abstract URL: Click here to view abstract

9. Sensor-augmented insulin pump therapy: results of the first randomized treat-to-target study.

Author: Hirsch IB; Abelseth J; Bode BW; Fischer JS; Kaufman FR; Mastrototaro J; Parkin CG; Wolpert HA; Buckingham BA;
Institution: University of Washington Medical Center-Roosevelt, Seattle, Washington 98105, USA. ihirsch@u.washington.edu
Journal: Diabetes Technol Ther. 2008 Oct;10(5):377-83.
Abstract URL: Click here to view abstract

10. Autoimmune diabetes in adults: lessons from the UKPDS.

Author: Desai M; Clark A;
Institution: Diabetes Research Laboratories, Oxford Centre for Diabetes Endocrinology and Metabolism, Oxford, UK.
Journal: Diabet Med. 2008 Aug;25 Suppl 2:30-4.
Abstract URL: Click here to view abstract

11. Continuous glucose monitoring and intensive treatment of type 1 diabetes.

Author: Tamborlane WV; Beck RW; Bode BW; Buckingham B; Chase HP; Clemons R; Fiallo-Scharer R; Fox LA; Gilliam LK; Hirsch IB; Huang ES; Kollman C; Kowalski AJ; Laffel L; Lawrence JM; Lee J; Mauras N; O'Grady M; Ruedy KJ; Tansey M; Tsalikian E; Weinzimer S; Wilson DM; Wolpert H; Wysocki T; Xing D;
Institution
Journal: N Engl J Med. 2008 Oct 2;359(14):1464-76. Epub 2008 Sep 8.
Abstract URL: Click here to view abstract

12. Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials.

Author: Chaturvedi N; Porta M; Klein R; Orchard T; Fuller J; Parving HH; Bilous R; Sjolie AK;
Institution: International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College Healthcare NHS Trust, London, UK.
Journal: Lancet. 2008 Oct 18;372(9647):1394-402. Epub 2008 Sep 25.
Abstract URL: Click here to view abstract

13. GAD treatment and insulin secretion in recent-onset type 1 diabetes.

Author: Ludvigsson J; Faresjo M; Hjorth M; Axelsson S; Cheramy M; Pihl M; Vaarala O; Forsander G; Ivarsson S; Johansson C; Lindh A; Nilsson NO; Aman J; Ortqvist E; Zerhouni P; Casas R;
Institution: Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, Linkoping, Sweden. johnny.ludvigsson@lio.se
Journal: N Engl J Med. 2008 Oct 30;359(18):1909-20. Epub 2008 Oct 8.
Abstract URL: Click here to view abstract

14. Effect of adjunct metformin treatment in patients with type-1 diabetes and persistent inadequate glycaemic control. A randomized study.

Author: Lund SS; Tarnow L; Astrup AS; Hovind P; Jacobsen PK; Alibegovic AC; Parving I; Pietraszek L; Frandsen M; Rossing P; Parving HH; Vaag AA;
Institution: Steno Diabetes Center, Gentofte, Denmark. sqrl@steno.dk
Journal: PLoS ONE. 2008;3(10):e3363. Epub 2008 Oct 9.
Abstract URL: Click here to view abstract

15. The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease.

Author: Belch J; MacCuish A; Campbell I; Cobbe S; Taylor R; Prescott R; Lee R; Bancroft J; MacEwan S; Shepherd J; Macfarlane P; Morris A; Jung R; Kelly C; Connacher A; Peden N; Jamieson A; Matthews D; Leese G; McKnight J; O'Brien I; Semple C; Petrie J; Gordon D; Pringle S; MacWalter R;
Institution: Institute of Cardiovascular Research, University of Dundee, Ninewells Hospital, Dundee DD1 9SY. J.J.F.Belch@dundee.ac.uk
Journal: BMJ. 2008 Oct 16;337:a1840. doi: 10.1136/bmj.a1840.
Abstract URL: Click here to view abstract

16. Health-related quality of life of children and adolescents with type 1 or type 2 diabetes mellitus: SEARCH for Diabetes in Youth Study.

Author: Naughton MJ; Ruggiero AM; Lawrence JM; Imperatore G; Klingensmith GJ; Waitzfelder B; McKeown RE; Standiford DA; Liese AD; Loots B;
Institution: Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, 2000 W First St, Winston-Salem, NC 27104, USA. naughton@wfubmc.edu
Journal: Arch Pediatr Adolesc Med. 2008 Jul;162(7):649-57.
Abstract URL: Click here to view abstract

17. Establishing glycaemic control with continuous subcutaneous insulin infusion in children and adolescents with type 1 diabetes: experience of the PedPump Study in 17 countries.

Author: Danne T; Battelino T; Jarosz-Chobot P; Kordonouri O; Pankowska E; Ludvigsson J; Schober E; Kaprio E; Saukkonen T; Nicolino M; Tubiana-Rufi N; Klinkert C; Haberland H; Vazeou A; Madacsy L; Zangen D; Cherubini V; Rabbone I; Toni S; de Beaufort C; Bakker-van Waarde W; van den Berg N; Volkov I; Barrio R; Hanas R; Zumsteg U; Kuhlmann B; Aebi C; Schumacher U; Gschwend S; Hindmarsh P; Torres M; Shehadeh N; Phillip M;
Institution: Kinderkrankenhaus auf der Bult, Hanover, Janusz-Korczak-Allee 12, 30173 Hanover, Germany. danne@hka.de
Journal: Diabetologia. 2008 Sep;51(9):1594-601. Epub 2008 Jul 1.
Abstract URL: Click here to view abstract

18. Long-term efficacy and safety of insulin detemir compared to Neutral Protamine Hagedorn insulin in patients with Type 1 diabetes using a treat-to-target basal-bolus regimen with insulin aspart at meals: a 2-year, randomized, controlled trial.

Author: Bartley PC; Bogoev M; Larsen J; Philotheou A;
Institution: Department of Medicine, University of Queensland, Australia. p.bartley@uq.edu.au
Journal: Diabet Med. 2008 Apr;25(4):442-9.
Abstract URL: Click here to view abstract

19. Insulin intervention in slowly progressive insulin-dependent (type 1) diabetes mellitus.

Author: Maruyama T; Tanaka S; Shimada A; Funae O; Kasuga A; Kanatsuka A; Takei I; Yamada S; Harii N; Shimura H; Kobayashi T;
Institution: Third Department of Internal Medicine, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, Japan.
Journal: J Clin Endocrinol Metab. 2008 Jun;93(6):2115-21. Epub 2008 Apr 8.
Abstract URL: Click here to view abstract

20. Intensive insulin therapy in preschool-aged diabetic children: from multiple daily injections to continuous subcutaneous insulin infusion through indwelling catheters.

Author: Rabbone I; Bobbio A; Di Gianni V; Sacchetti C; Cerutti F;
Institution: Department of Paediatrics, University of Turin, 10126 Turin, Italy. ivana.rabbone@unito.it
Journal: J Endocrinol Invest. 2008 Mar;31(3):193-5.
Abstract URL: Click here to view abstract

21. Islet transplantation for brittle type 1 diabetes: the UIC protocol.

Author: Gangemi A; Salehi P; Hatipoglu B; Martellotto J; Barbaro B; Kuechle JB; Qi M; Wang Y; Pallan P; Owens C; Bui J; West D; Kaplan B; Benedetti E; Oberholzer J;
Institution: Division of Transplantation/Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA.
Journal: Am J Transplant. 2008 Jun;8(6):1250-61. Epub 2008 Apr 29.
Abstract URL: Click here to view abstract

22. Insulin glargine maintains equivalent glycemic control and better lipometabolic control than NPH insulin in type 1 diabetes patients who missed a meal.

Author: Rosak C; Jung R; Hofmann U;
Institution: Department of Diabetology and Metabolic Disorders, Carl von Noorden Klinikum Sachsenhausen, Frankfurt, Germany. profrosak@gmx.net
Journal: Horm Metab Res. 2008 Aug;40(8):544-8. Epub 2008 May 20.
Abstract URL: Click here to view abstract

23. Optimizing postprandial glycemia in pediatric patients with type 1 diabetes using insulin pump therapy: impact of glycemic index and prandial bolus type.

Author: O'Connell MA; Gilbertson HR; Donath SM; Cameron FJ;
Institution: Department of Endocrinology and Diabetes, Centre for Hormone Research, Royal Children's Hospital, Murdoch Childrens Research Institute, Melbourne, Australia.
Journal: Diabetes Care. 2008 Aug;31(8):1491-5. Epub 2008 May 28.
Abstract URL: Click here to view abstract

24. Multisystemic therapy for adolescents with poorly controlled type 1 diabetes: reduced diabetic ketoacidosis admissions and related costs over 24 months.

Author: Ellis D; Naar-King S; Templin T; Frey M; Cunningham P; Sheidow A; Cakan N; Idalski A;
Institution: Carmen and Anne Adams Department of Pediatrics, Wayne State University, Detroit, Michigan, USA. dellis@med.wayne.edu
Journal: Diabetes Care. 2008 Sep;31(9):1746-7. Epub 2008 Jun 19.
Abstract URL: Click here to view abstract

25. Risk of myocardial infarction in men and women with type 2 diabetes in the UK: a cohort study using the General Practice Research Database.

Author: Mulnier HE; Seaman HE; Raleigh VS; Soedamah-Muthu SS; Colhoun HM; Lawrenson RA; de Vries CS;
Institution: Postgraduate Medical School, University of Surrey, Daphne Jackson Road, Manor Park, Guildford, Surrey GU2 7WG, UK. h.mulnier@surrey.ac.uk
Journal: Diabetologia. 2008 Sep;51(9):1639-45. Epub 2008 Jun 26.
Abstract URL: Click here to view abstract

26. Insulin glargine versus intermediate-acting insulin as the basal component of multiple daily injection regimens for adolescents with type 1 diabetes mellitus.

Author: Chase HP; Arslanian S; White NH; Tamborlane WV;
Institution: Barbara Davis Center, University of Colorado, Aurora, CO 80045-6511, USA. peter.chase@uchsc.edu
Journal: J Pediatr. 2008 Oct;153(4):547-53. Epub 2008 Jun 27.
Abstract URL: Click here to view abstract

27. Glargine versus NPH insulin: efficacy in comparison with insulin aspart in a basal bolus regimen in type 1 diabetes--the glargine and aspart study (GLASS) a randomised cross-over study.

Author: Chatterjee S; Jarvis-Kay J; Rengarajan T; Lawrence IG; McNally PG; Davies MJ;
Institution: Department of Diabetes, University Hospitals of Leicester, Leicester, UK. sudesna.chatterjee@uhl-tr.nhs.uk
Journal: Diabetes Res Clin Pract. 2007 Aug;77(2):215-22. Epub 2006 Dec 1.
Abstract URL: Click here to view abstract

28. A pilot trial in pediatrics with the sensor-augmented pump: combining real-time continuous glucose monitoring with the insulin pump.

Author: Halvorson M; Carpenter S; Kaiserman K; Kaufman FR;
Institution: Division of Endocrinology and Metabolism, Childrens Hospital Los Angeles, Los Angeles, California 90027, USA. mhalvorson@chla.usc.edu
Journal: J Pediatr. 2007 Jan;150(1):103-105.e1.
Abstract URL: Click here to view abstract

29. Impact of physical activity on cardiovascular risk factors in children with type 1 diabetes: a multicenter study of 23,251 patients.

Author: Herbst A; Kordonouri O; Schwab KO; Schmidt F; Holl RW;
Institution: Pediatrics, Hospital of Leverkusen, Am Gesundheitspark 11, 51375 Leverkusen, Germany. herbst@klinikum-lev.de
Journal: Diabetes Care. 2007 Aug;30(8):2098-100. Epub 2007 Apr 27.

30. The effect of intensive diabetes treatment on resting heart rate in type 1 diabetes: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study.

Author: Paterson AD; Rutledge BN; Cleary PA; Lachin JM; Crow RS;
Institution: Program in Genetics and Genomic Biology, The Hospital for Sick Children, TMDT Building East Tower, Room 15-707, 101 College St., Toronto, ON M5G 1L7, Canada. andrew.paterson@utoronto.ca
Journal: Diabetes Care. 2007 Aug;30(8):2107-12. Epub 2007 Apr 27.
Abstract URL: Click here to view abstract

31. Long-term effect of diabetes and its treatment on cognitive function.

Author: Jacobson AM; Musen G; Ryan CM; Silvers N; Cleary P; Waberski B; Burwood A; Weinger K; Bayless M; Dahms W; Harth J;
Institution
Journal: N Engl J Med. 2007 May 3;356(18):1842-52.
Abstract URL: Click here to view abstract

32. A randomized pilot study in Type 1 diabetes complicated by severe hypoglycaemia, comparing rigorous hypoglycaemia avoidance with insulin analogue therapy, CSII or education alone.

Author: Thomas RM; Aldibbiat A; Griffin W; Cox MA; Leech NJ; Shaw JA;
Institution: Newcastle Diabetes Centre, Newcastle upon Tyne, UK.
Journal: Diabet Med. 2007 Jul;24(7):778-83. Epub 2007 May 29.
Abstract URL: Click here to view abstract

33. Diabetes personal trainer outcomes: short-term and 1-year outcomes of a diabetes personal trainer intervention among youth with type 1 diabetes.

Author: Nansel TR; Iannotti RJ; Simons-Morton BG; Cox C; Plotnick LP; Clark LM; Zeitzoff L;
Institution: Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA. nanselt@mail.nih.gov
Journal: Diabetes Care. 2007 Oct;30(10):2471-7. Epub 2007 Jul 9.
Abstract URL: Click here to view abstract

34. Diabetic nephropathy in 27,805 children, adolescents, and adults with type 1 diabetes: effect of diabetes duration, A1C, hypertension, dyslipidemia, diabetes onset, and sex.

Author: Raile K; Galler A; Hofer S; Herbst A; Dunstheimer D; Busch P; Holl RW;
Institution: Department of Pediatric Endocrinology and Diabetes, Charite Children's Hospital, Augustenburger Platz 1, 13353 Berlin, Germany. klemens.raile@charite.de
Journal: Diabetes Care. 2007 Oct;30(10):2523-8. Epub 2007 Jul 13.
Abstract URL: Click here to view abstract

35. The effects of weight status on treatment outcomes in a randomized clinical trial of multisystemic therapy for adolescents with type 1 diabetes and chronically poor metabolic control.

Author: Cakan N; Ellis DA; Templin T; Frey M; Naar-King S;
Institution: Carman and Ann Adams Department of Pediatrics, Wayne State University, Detroit, MI, USA. ncakan@med.wayne.edu
Journal: Pediatr Diabetes. 2007 Aug;8(4):206-13.
Abstract URL: Click here to view abstract

36. The transition to young adulthood in youth with type 1 diabetes on intensive treatment.

Author: Insabella G; Grey M; Knafl G; Tamborlane W;
Institution: Yale University School of Nursing, New Haven, CT, USA.
Journal: Pediatr Diabetes. 2007 Aug;8(4):228-34.
Abstract URL: Click here to view abstract

37. Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus.

Author: Voltarelli JC; Couri CE; Stracieri AB; Oliveira MC; Moraes DA; Pieroni F; Coutinho M; Malmegrim KC; Foss-Freitas MC; Simoes BP; Foss MC; Squiers E; Burt RK;
Institution: Department of Clinical Medicine, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil. jcvoltar@fmrp.usp.br
Journal: JAMA. 2007 Apr 11;297(14):1568-76.
Abstract URL: Click here to view abstract

38. Levothyroxine in euthyroid autoimmune thyroiditis and type 1 diabetes: a randomized, controlled trial.

Author: Karges B; Muche R; Knerr I; Ertelt W; Wiesel T; Hub R; Neu A; Klinghammer A; Aufschild J; Rapp A; Schirbel A; Boehm BO; Debatin KM; Heinze E; Karges W;
Institution: Division of Pediatric Endocrinology and Diabetes, University Children's Hospital, University of Ulm, Eythstrasse 24, D-89075 Ulm, Germany. beate.karges@uniklinik-ulm.de
Journal: J Clin Endocrinol Metab. 2007 May;92(5):1647-52. Epub 2007 Feb 13.
Abstract URL: Click here to view abstract

39. Changes in the glycemic profiles of women with type 1 and type 2 diabetes during pregnancy.

Author: Murphy HR; Rayman G; Duffield K; Lewis KS; Kelly S; Johal B; Fowler D; Temple RC; Murphy HR; Rayman G; Duffield K; Lewis KS; Kelly S; Johal B; Fowler D; Temple RC;
Institution: Ipswich Hospital NHS Trust, Ipswich IP4 5PD, UK. helen.murphy@ipswichhospital.nhs.uk
Journal: Diabetes Care. 2007 Nov;30(11):2785-91. Epub 2007 Jul 31.
Abstract URL: Click here to view abstract