Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus > What Your Doctor is Reading About Type 2 Diabetes Mellitus > Clinical Trials

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Clinical Trials

1. Effects of clopidogrel and aspirin in combination versus aspirin alone on platelet activation and major receptor expression in diabetic patients: the PLavix Use for Treatment Of Diabetes (PLUTO-Diabetes) trial.

Author: Serebruany VL; Malinin AI; Pokov A; Barsness G; Hanley DF;
Institution: HeartDrug Research Laboratories, Towson, MD 21204, USA. Heartdrug@aol.com
Journal: Am Heart J. 2008 Jan;155(1):93.e1-7. Epub 2007 Nov 26.
Abstract URL: Click here to view abstract

2. Vitamin E supplementation reduces cardiovascular events in a subgroup of middle-aged individuals with both type 2 diabetes mellitus and the haptoglobin 2-2 genotype: a prospective double-blinded clinical trial.

Author: Milman U; Blum S; Shapira C; Aronson D; Miller-Lotan R; Anbinder Y; Alshiek J; Bennett L; Kostenko M; Landau M; Keidar S; Levy Y; Khemlin A; Radan A; Levy AP;
Institution: Clalit Health Services, Haifa, Israel.
Journal: Arterioscler Thromb Vasc Biol. 2008 Feb;28(2):341-7. Epub 2007 Nov 21.
Abstract URL: Click here to view abstract

3. Combination therapy of pioglitazone with voglibose improves glycemic control safely and rapidly in Japanese type 2-diabetic patients on hemodialysis.

Author: Abe M; Kikuchi F; Kaizu K; Matsumoto K;
Institution: Division of Nephrology and Endocrinology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan. mabe@med.nihon-u.ac.jp
Journal: Clin Nephrol. 2007 Nov;68(5):287-94.
Abstract URL: Click here to view abstract

4. Effect of a multifactorial intervention on mortality in type 2 diabetes.

Author: Goede P; Lund-Andersen H; Parving HH; Pedersen O; Gaede P; Lund-Andersen H; Parving HH; Pedersen O;
Institution: Steno Diabetes Center, Copenhagen, Denmark.
Journal: N Engl J Med. 2008 Feb 7;358(6):580-91.
Abstract URL: Click here to view abstract

5. Differential effect of pioglitazone (PGZ) and rosiglitazone (RGZ) on postprandial glucose and lipid metabolism in patients with type 2 diabetes mellitus: a prospective, randomized crossover study.

Author: Chappuis B; Braun M; Stettler C; Allemann S; Diem P; Lumb PJ; Wierzbicki AS; James R; Christ ER;
Institution: Division of Endocrinology, Diabetes and Clinical Nutrition, University Hospital of Berne, Inselspital, CH-3010 Bern, Switzerland.
Journal: Diabetes Metab Res Rev. 2007 Jul;23(5):392-9.
Abstract URL: Click here to view abstract

6. Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes.

Author: Goldstein BJ; Feinglos MN; Lunceford JK; Johnson J; Williams-Herman DE;
Institution: Division of Endocrinology, Diabetes, and Metabolic Diseases, Jefferson Medical College, Philadelphia, Pennsylvania, USA.
Journal: Diabetes Care. 2007 Aug;30(8):1979-87. Epub 2007 May 7.
Abstract URL: Click here to view abstract

7. Beneficial effects of combined treatment with rosiglitazone and exercise on cardiovascular risk factors in patients with type 2 diabetes.

Author: Kadoglou NP; Iliadis F; Liapis CD; Perrea D; Angelopoulou N; Alevizos M;
Institution: 1st Propedeutic Department Internal Medicine, AHEPA University Hospital, Thessaloniki, Greece. nikoskad@yahoo.com
Journal: Diabetes Care. 2007 Sep;30(9):2242-4. Epub 2007 Jun 22.

8. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis.

Author: Kearney PM; Blackwell L; Collins R; Keech A; Simes J; Peto R; Armitage J; Baigent C; Kearney PM; Blackwell L; Collins R; Keech A; Simes J; Peto R; Armitage J; Baigent C; Kearney PM; Blackwell L; Collins R; Keech A; Simes J; Peto R; Armitage J; Baigent C;
Institution
Journal: Lancet. 2008 Jan 12;371(9607):117-25.
Abstract URL: Click here to view abstract

9. Factors influencing pregnancy outcome in women with type 2 versus type 1 diabetes mellitus.

Author: Gonzalez-Gonzalez NL; Ramirez O; Mozas J; Melchor J; Armas H; Garcia-Hernandez JA; Caballero A; Hernandez M; Diaz-Gomez MN; Jimenez A; Parache J; Bartha JL;
Institution: Department of Obstetrics and Gynecology, University Hospital of the Canary Islands, Tenerife, Spain. ngonzalezg@sego.es
Journal: Acta Obstet Gynecol Scand. 2008;87(1):43-9.
Abstract URL: Click here to view abstract

10. Long-term follow-up after tight control of blood pressure in type 2 diabetes.

Author: Holman RR; Paul SK; Bethel MA; Neil HA; Matthews DR;
Institution: Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Headington, Oxford OX3 7LJ, United Kingdom. rury.holman@dtu.ox.ac.uk
Journal: N Engl J Med. 2008 Oct 9;359(15):1565-76. Epub 2008 Sep 10.
Abstract URL: Click here to view abstract

Next: Centers of Research for Type 2 Diabetes Mellitus

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"I found the Guidebook very comprehensive and written in a professional and clear style. I would recommend your books to anyone who has a problem and needs to go to a doctor. Trusting your health issues in the hands of a doctor who may or may not be good or professional is no longer acceptable. I found that my father-in-law's doctor does not actually know about many of the studies described in the book even though he is considered to be one of the "specialists" in this domain."

M.S., Sydney, Australia