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Polycystic Ovary Syndrome > What Your Doctor is Reading About Polycystic Ovary Syndrome > Clinical Trials

Clinical Trials

1. Association of pioglitazone treatment with decreased bone mineral density in obese premenopausal patients with polycystic ovary syndrome: a randomized, placebo-controlled trial.

Author: Glintborg D; Andersen M; Hagen C; Heickendorff L; Hermann AP;
Institution: Department of Endocrinology and Metabolism, Odense University Hospital, Klovervaenget 6, Odense C, Denmark. dorte.glintborg@dadlnet.dk
Journal: J Clin Endocrinol Metab. 2008 May;93(5):1696-701. Epub 2008 Feb 19.
Abstract URL: Click here to view abstract

2. Effect of sibutramine on weight reduction in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial.

Author: Lindholm A; Bixo M; Bjorn I; Wolner-Hanssen P; Eliasson M; Larsson A; Johnson O; Poromaa IS;
Institution: Department of Obstetrics and Gynecology, Sunderby Hospital, Lulea, Sweden. asa.lindholm@nll.se
Journal: Fertil Steril. 2008 May;89(5):1221-8. Epub 2007 Jul 2.
Abstract URL: Click here to view abstract

3. Long-term follow up of women with laparoscopic ovarian diathermy for women with clomiphene-resistant polycystic ovarian syndrome.

Author: Mohiuddin S; Bessellink D; Farquhar C;
Institution: National Women's Health, Auckland City Hospital, University of Auckland, New Zealand.
Journal: Aust N Z J Obstet Gynaecol. 2007 Dec;47(6):508-11.
Abstract URL: Click here to view abstract

4. Dietary intervention versus metformin to improve the reproductive outcome in women with polycystic ovary syndrome. A prospective comparative study.

Author: Qublan HS; Yannakoula EK; Al-Qudah MA; El-Uri FI;
Institution: Department of Obstetrics & Gynecology, Royal Medical Services, Irbid, Aidoun, PO Box 97, Jordan. hqublan@yahoo.com
Journal: Saudi Med J. 2007 Nov;28(11):1694-9.
Abstract URL: Click here to view abstract

5. Unilateral ovarian drilling in polycystic ovarian syndrome: a prospective randomized study.

Author: Youssef H; Atallah MM;
Institution: Department of Obstetrics and Gynecology, Mansoura University Hospital, Mansoura, Egypt. kaainih@link.net
Journal: Reprod Biomed Online. 2007 Oct;15(4):457-62.
Abstract URL: Click here to view abstract

6. Triggering final oocyte maturation using different doses of human chorionic gonadotropin: a randomized pilot study in patients with polycystic ovary syndrome treated with gonadotropin-releasing hormone antagonists and recombinant follicle-stimulating hormone.

Author: Kolibianakis EM; Papanikolaou EG; Tournaye H; Camus M; Van Steirteghem AC; Devroey P;
Institution: Centre for Reproductive Medicine, Vrije Universiteit Brussel, Brussels, Belgium. stratis.kolibianakis@irg.gr
Journal: Fertil Steril. 2007 Nov;88(5):1382-8. Epub 2007 Apr 18.
Abstract URL: Click here to view abstract

7. Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome.

Author: Legro RS; Barnhart HX; Schlaff WD; Carr BR; Diamond MP; Carson SA; Steinkampf MP; Coutifaris C; McGovern PG; Cataldo NA; Gosman GG; Nestler JE; Giudice LC; Leppert PC; Myers ER; Legro RS; Barnhart HX; Schlaff WD; Carr BR; Diamond MP; Carson SA; Steinkampf MP; Coutifaris C; McGovern PG; Cataldo NA; Gosman GG; Nestler JE; Giudice LC; Leppert PC; Myers ER;
Institution: Department of Obstetrics and Gynecology, Pennsylvania State University College of Medicine, M.S. Hershey Medical Center, Hershey, PA 17033, USA. rsl1@psu.edu
Journal: N Engl J Med. 2007 Feb 8;356(6):551-66.
Abstract URL: Click here to view abstract

8. Effects of simvastatin and oral contraceptive agent on polycystic ovary syndrome: prospective, randomized, crossover trial.

Author: Banaszewska B; Pawelczyk L; Spaczynski RZ; Dziura J; Duleba AJ;
Institution: Department of Gynecology/Obstetrics, Poznan University of Medical Sciences, Poznan, Poland.
Journal: J Clin Endocrinol Metab. 2007 Feb;92(2):456-61. Epub 2006 Nov 14.
Abstract URL: Click here to view abstract

9. The effects of metformin and rosiglitazone, alone and in combination, on the ovary and endometrium in polycystic ovary syndrome.

Author: Legro RS; Zaino RJ; Demers LM; Kunselman AR; Gnatuk CL; Williams NI; Dodson WC;
Institution: Department of Obstetrics and Gynecology, The Pennsylvania State University College of Medicine, Hershey, PA, USA. RSL1@psu.edu
Journal: Am J Obstet Gynecol. 2007 Apr;196(4):402.e1-10; discussion 402.e10-1.
Abstract URL: Click here to view abstract

10. N-Acetyl cysteine and clomiphene citrate for induction of ovulation in polycystic ovary syndrome: a cross-over trial.

Author: Badawy A; State O; Abdelgawad S;
Institution: Department of Obstetrics and Gynaecology, Mansoura University, Mansoura, Egypt. ambadawy@yahoo.com
Journal: Acta Obstet Gynecol Scand. 2007;86(2):218-22.
Abstract URL: Click here to view abstract

11. Homocysteine levels are unaffected by metformin treatment in both nonpregnant and pregnant women with polycystic ovary syndrome.

Author: Carlsen SM; Kjotrod S; Vanky E; Romundstad P;
Institution: Department of Community Medicine and General Practice, Norwegian University of Science and Technology, Trondheim, Norway. sven.carlsen@ntnu.no
Journal: Acta Obstet Gynecol Scand. 2007;86(2):145-50.
Abstract URL: Click here to view abstract

12. Effects of medical therapy on insulin resistance and the cardiovascular system in polycystic ovary syndrome.

Author: Meyer C; McGrath BP; Teede HJ;
Institution: Centre for Vascular Health, Department of Medicine, Monash University, Melbourne, Victoria, Australia.
Journal: Diabetes Care. 2007 Mar;30(3):471-8.
Abstract URL: Click here to view abstract

13. Comparison of clomiphene citrate, metformin, or the combination of both for first-line ovulation induction and achievement of pregnancy in 154 women with polycystic ovary syndrome.

Author: Neveu N; Granger L; St-Michel P; Lavoie HB; Neveu N; Granger L; St-Michel P; Lavoie HB;
Institution: PROCREA Cliniques, Mont-Royal, Quebec, Canada.
Journal: Fertil Steril. 2007 Jan;87(1):113-20. Epub 2006 Nov 1.
Abstract URL: Click here to view abstract

14. Rosiglitazone treatment alleviates inflammation and improves liver function in overweight women with polycystic ovary syndrome: a randomized placebo-controlled study.

Author: Rautio K; Tapanainen JS; Ruokonen A; Morin-Papunen LC;
Institution: Department of Obstetrics and Gynecology, University Hospital of Oulu, Oulu, Finland.
Journal: Fertil Steril. 2007 Jan;87(1):202-6. Epub 2006 Oct 30.
Abstract URL: Click here to view abstract

15. Evaluation of ovarian adhesion formation after laparoscopic ovarian drilling by second-look minilaparoscopy.

Author: Mercorio F; Mercorio A; Di Spiezio Sardo A; Barba GV; Pellicano M; Nappi C;
Institution: Department of Gynaecology and Obstetrics, and Pathophysiology of Human Reproduction, University of Naples Federico II, Naples, Italy. fmercorio@libero.it
Journal: Fertil Steril. 2008 May;89(5):1229-33. Epub 2007 Aug 6.
Abstract URL: Click here to view abstract

16. Anastrozole or letrozole for ovulation induction in clomiphene-resistant women with polycystic ovarian syndrome: a prospective randomized trial.

Author: Badawy A; Mosbah A; Shady M;
Institution: Department of Obstetrics & Gynecology, Mansoura University, Mansoura, Egypt. ambadawy@yahoo.com
Journal: Fertil Steril. 2008 May;89(5):1209-12. Epub 2007 Aug 8.
Abstract URL: Click here to view abstract

17. Obesity, weight loss, and the polycystic ovary syndrome: effect of treatment with diet and orlistat for 24 weeks on insulin resistance and androgen levels.

Author: Panidis D; Farmakiotis D; Rousso D; Kourtis A; Katsikis I; Krassas G;
Institution: 2nd Department of Obstetrics and Gynecology, Division of Human Reproduction, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Journal: Fertil Steril. 2008 Apr;89(4):899-906. Epub 2007 Nov 5.
Abstract URL: Click here to view abstract

18. Unilateral laparoscopic ovarian diathermy in infertile women with clomiphene citrate-resistant polycystic ovary syndrome.

Author: Al-Mizyen E; Grudzinskas JG; Al-Mizyen E; Grudzinskas JG;
Institution: Department of Obstetrics and Gynaecology, St. Bartholomew's and the Royal London School of Medicine and Dentistry, London, United Kingdom. drebtisam@hotmail.com
Journal: Fertil Steril. 2007 Dec;88(6):1678-80. Epub 2007 Apr 23.
Abstract URL: Click here to view abstract

19. Cardiovascular risk factors are reduced with a low dose of acarbose in obese patients with polycystic ovary syndrome.

Author: Penna IA; Canella PR; Vieira CS; Silva de Sa MF; Reis RM; Ferriani RA;
Institution: Department of Obstetrics and Gynecology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil; Gynecology Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Journal: Fertil Steril. 2007 Apr 5;.
Abstract URL: Click here to view abstract