Saturday, September 6, 2008 - 2:12PM EST

Clinical Trials

1. Effects of unilateral subthalamic deep brain stimulation on contralateral arm sequential movements in Parkinson's disease.

Author
Agostino R; Dinapoli L; Modugno N; Iezzi E; Romanelli P; Berardelli A;
Institution
Department of Neurological Sciences and Neuromed Institute, University of Rome La Sapienza, Rome, Italy.
Journal
J Neurol Neurosurg Psychiatry. 2008 Jan;79(1):76-8. Epub 2007 Aug 6.
Abstract URL
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2. Exhaustive, one-year follow-up of subthalamic nucleus deep brain stimulation in a large, single-center cohort of parkinsonian patients.

Author
Tir M; Devos D; Blond S; Touzet G; Reyns N; Duhamel A; Cottencin O; Dujardin K; Cassim F; Destee A; Defebvre L; Krystkowiak P;
Institution
Department of Neurology, Salengro Hospital, Lille University Medical Centre, Lille, France.
Journal
Neurosurgery. 2007 Aug;61(2):297-304; discussion 304-5.
Abstract URL
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3. Cognitive declines following bilateral subthalamic nucleus deep brain stimulation for the treatment of Parkinson's disease.

Author
York MK; Dulay M; Macias A; Levin HS; Grossman R; Simpson R; Jankovic J;
Institution
Baylor College of Medicine, Department of Neurology, 6501 Fannin, NB302, Houston, Texas 77030, USA. myork@bcm.edu
Journal
J Neurol Neurosurg Psychiatry. 2008 Jul;79(7):789-95. Epub 2007 Oct 26.
Abstract URL
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4. Safety and efficacy of subthalamic nucleus deep brain stimulation performed with limited intraoperative mapping for treatment of Parkinson's disease.

Author
Tabbal SD; Revilla FJ; Mink JW; Schneider-Gibson P; Wernle AR; de Erausquin GA; Perlmutter JS; Rich KM; Dowling JL;
Institution
Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. tabbals@neuro.wustl.edu
Journal
Neurosurgery. 2007 Sep;61(3 Suppl):119-27; discussion 127-9.
Abstract URL
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5. Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial.

Author
Kaplitt MG; Feigin A; Tang C; Fitzsimons HL; Mattis P; Lawlor PA; Bland RJ; Young D; Strybing K; Eidelberg D; During MJ;
Institution
Department of Neurological Surgery, Weill Medical College of Cornell University, New York, NY, USA.
Journal
Lancet. 2007 Jun 23;369(9579):2097-105.
Abstract URL
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6. Results from a phase I safety trial of hAADC gene therapy for Parkinson disease.

Author
Eberling JL; Jagust WJ; Christine CW; Starr P; Larson P; Bankiewicz KS; Aminoff MJ;
Institution
Department of Molecular Imaging and Neuroscience, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. jleberling@lbl.gov
Journal
Neurology. 2008 May 20;70(21):1980-3. Epub 2008 Apr 9.
Abstract URL
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7. Randomized, blind, controlled trial of transdermal rotigotine in early Parkinson disease.

Author
Watts RL; Jankovic J; Waters C; Rajput A; Boroojerdi B; Rao J;
Institution
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35233-0017, USA. rlwatts@uab.edu
Journal
Neurology. 2007 Jan 23;68(4):272-6. Epub 2007 Jan 3.
Abstract URL
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8. Zonisamide improves motor function in Parkinson disease: a randomized, double-blind study.

Author
Murata M; Hasegawa K; Kanazawa I;
Institution
Department of Neurology, Musashi Hospital, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashimachi, Kodaira, Tokyo 187-8551, Japan. mihom@ncnp.go.jp
Journal
Neurology. 2007 Jan 2;68(1):45-50.
Abstract URL
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9. A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease.

Author
Institution
University of Rochester Medical Center, 1351 Mt. Hope Ave., Ste. 223, Rochester, NY 14620, USA.
Journal
Neurology. 2007 Jan 2;68(1):20-8.
Abstract URL
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10. Neurosurgery at an earlier stage of Parkinson disease: a randomized, controlled trial.

Author
Schupbach WM; Maltete D; Houeto JL; du Montcel ST; Mallet L; Welter ML; Gargiulo M; Behar C; Bonnet AM; Czernecki V; Pidoux B; Navarro S; Dormont D; Cornu P; Agid Y;
Institution
Centre d'Investigation Clinique, Groupe Hospitalier Pitie-Salpetriere, Paris, France.
Journal
Neurology. 2007 Jan 23;68(4):267-71. Epub 2006 Dec 6.
Abstract URL
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