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Investigation continues regarding the possibility of an autoimmune mechanism in the development of RSD which could ultimately influence treatment for this condition. For more information, please click on the following link: http://www.ncbi.nlm.nih.gov/pubmed/17804544

There is evidence from several studies that a daily dose of 500 mg of Vitamin C may prevent development of RSD if initiated as soon as the diagnosis of a wrist fracture is determined. For more information about this development, please click on the following link: http://www.ncbi.nlm.nih.gov/pubmed/17606778

Intensive research continues regarding RSD in children and adolescents which is thought to be severely underdiagnosed and misunderstood. Read about the latest information which was published in the Journal of Pediatric Orthopedics in 2007 by clicking on the following link: http://www.ncbi.nlm.nih.gov/pubmed/17585269

Scientists are investigating the use of transdermal fentanyl patches for pain relief in RSD. The following link provides more information: http://www.ncbi.nlm.nih.gov/pubmed/17883740

Deep brain stimulation is being investigated as a treatment option for people with chronic pain syndromes. To read more about this developing relationship, please click on the following link: http://www.ncbi.nlm.nih.gov/pubmed/17341052

A pilot study was published in the Clinical Journal of Pain regarding the efficacy of a drug called Memantine in patients with RSD. Results from this small study indicate a reduction in the level of pain, an improvement of motor symptoms, and improvement of autonomic changes. To read more about this study, please click on the following link: http://www.ncbi.nlm.nih.gov/pubmed/17314583

Researchers at Duke University Medical Center are investigating a treatment called motor cortex stimulation for intractable pain. It has proven successful for some patients with trigeminal neuralgia and poststroke pain, and scientists are studying the potential for its effectiveness for neuropathic and central pain conditions. To read more about this treatment, please click on the following link: http://www.ncbi.nlm.nih.gov/pubmed/17341051

Researchers at Robert Wood Johnson Medical School published an article in Pain Physician in 2005 in which they found that a 10-day infusion of low-dose ketamine was effective in reduction of pain in patients with severe RSD. To read more about this, please click on the following link: http://www.ncbi.nlm.nih.gov/pubmed/16850072 One of the authors published a study in 2007 regarding neurocognitive effects following ketamine infusion therapy in nine patients. You can see the results by clicking on the following link: http://www.ncbi.nlm.nih.gov/pubmed/17611073

If you are interested in information about clinical trials for RSD, please visit http://www.clinicaltrials.gov.