Wednesday, October 15, 2008 - 6:53PM EST

Introduction to Non-Small Cell Lung Cancer

Risk Factors for Lung Cancer

A risk factor is anything that increases a person's chances of getting a disease. The risk factors for lung cancer are well-defined and include:

  • Smoking - This is the leading risk factor for lung cancer. Tobacco smoke from cigarettes, cigars, and pipes accounts for about 80% of all lung cancer cases. If a person stops smoking at any age, the risk of lung cancer is significantly reduced. There is no scientific evidence that people who smoke "low-tar" cigarettes have a reduced risk for developing lung cancer.

  • Secondhand smoke - The risk of lung cancer is higher for people who are exposed to secondhand smoke even though they themselves may not be smokers.

  • Asbestos - Occupational or environmental exposure to asbestos is also recognized as a major risk factor for lung cancer. Exposure to asbestos causes a type of lung cancer called mesothelioma. The risk for developing mesothelioma is higher for smokers who have been exposed to asbestos.

  • Radon - Exposure to radon, an odorless radioactive gas that is a breakdown product of uranium, increases a person's risk for developing lung cancer.

  • Chemicals - Occupational or environmental exposure to certain chemicals increases the risk for developing lung cancer. Some of these chemicals include:

    • arsenic
    • nickel chromates
    • vinyl chloride
    • gasoline
    • diesel fuel exhaust
  • Air pollution - Environmental exposure to air pollutants, such as the combustion by-products of diesel and fossil fuels, may increase the risk for developing lung cancer.

  • Lung diseases - Scarring of lung tissue that can occur with some lung diseases such as tuberculosis or pneumonia may increase the risk for developing lung cancer.

  • Genetic factors - Some genetic factors may play a role in the development of lung cancer.

  • Gender - Women who are exposed to tobacco smoke may be at higher risk than men for developing lung cancer