Tuesday, December 2, 2008 - 11:51PM EST

Diagnosis of Liver Cancer

Signs and Symptoms of Liver Cancer

Unfortunately, the early diagnosis of liver cancer is difficult because most people with early-stage liver cancer are asymptomatic (do not exhibit clinical symptoms of the disease). Consequently, by the time signs and symptoms develop, the disease has already progressed to a more advanced stage. That's why liver cancer is sometimes referred to as a "silent" disease. The following signs and symptoms may be present in patients with liver cancer, however, these symptoms are not specific for liver cancer and may overlap with other conditions:

  • Abdominal pain
  • Generalized fatigue and weakness
  • Hepatomegaly - enlargement of the liver, which is the most common finding on physical examination in patients with liver cancer.
  • Unintentional weight loss
  • Poor appetite
  • Early satiety - a feeling of fullness in the stomach after consuming a small meal
  • Jaundice - a yellowish-green complexion of the skin and eyes caused by the accumulation of bilirubin in the liver.
  • Fever
  • Nausea and vomiting
  • Splenomegaly - enlargement of the spleen