Tuesday, December 2, 2008 - 11:15PM EST

Treatment Options for Liver Cancer

Novel Therapies for Liver Cancer

  • Oral fluoropyrimidines - Combination chemotherapy with tegafur and uracil is being investigated. A study published in 2001 in the Journal of Gastroenterology and Hepatology reported improved survival of patients with advanced-stage liver cancer following oral administration of tegafur/uracil. The article abstract can be viewed at: http://www.medifocus.com/abstracts.asp?gid=OC031&ID=11354285

  • Gemcitabine - This drug is being investigated in combination with other chemotherapeutic agents (e.g., doxorubicin, oxaliplatin) for the treatment of advanced-stage liver cancer.

  • Exatecan mesylate (DX-8951f) - This drug is a new topoisomerase-1 agent that is being investigated for the treatment of a variety of cancers including ovarian, breast, colon, and lung cancer and may also have potential as a systemic treatment for patients with advanced-stage liver cancer.

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