Clinical Trials

1. Dose-escalation of filgrastim does not improve efficacy: clinical tolerability and long-term follow-up on CALGB study 9141 adjuvant chemotherapy for node-positive breast cancer patients using dose-intensified doxorubicin plus cyclophosphamide followed by paclitaxel.

Author
Liu MC; Demetri GD; Berry DA; Norton L; Broadwater G; Robert NJ; Duggan D; Hayes DF; Henderson IC; Lyss A; Hopkins J; Kaufman PA; Marcom PK; Younger J; Lin N; Tkaczuk K; Winer EP; Hudis CA;
Institution
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3800 Reservoir Road NW, Washington, DC 20007-2198, USA. liumc@georgetown.edu
Journal
Cancer Treat Rev. 2008 May;34(3):223-30. Epub 2008 Jan 30.
Abstract URL
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2. Weekly docetaxel versus CMF as adjuvant chemotherapy for elderly breast cancer patients: safety data from the multicentre phase 3 randomised ELDA trial.

Author
Nuzzo F; Morabito A; De Maio E; Di Rella F; Gravina A; Labonia V; Landi G; Pacilio C; Piccirillo MC; Rossi E; D'Aiuto G; Thomas R; Gori S; Colozza M; De Placido S; Lauria R; Signoriello G; Gallo C; Perrone F; de Matteis A;
Institution
National Cancer Institute, Naples, Italy.
Journal
Crit Rev Oncol Hematol. 2008 May;66(2):171-80. Epub 2007 Dec 21.
Abstract URL
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3. Survival after adjuvant oophorectomy and tamoxifen in operable breast cancer in premenopausal women.

Author
Love RR; Van Dinh N; Quy TT; Linh ND; Tung ND; Shen TZ; Hade EM; Young GS; Jarjoura D;
Institution
Ohio State University, B402 Starling Loving Hall, 320 W 10th Ave, Columbus, OH 43210, USA. Richard.Love@osumc.edu
Journal
J Clin Oncol. 2008 Jan 10;26(2):253-7. Epub 2007 Dec 17.
Abstract URL
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4. Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial.

Author
Forbes JF; Cuzick J; Buzdar A; Howell A; Tobias JS; Baum M;
Institution
Journal
Lancet Oncol. 2008 Jan;9(1):45-53.
Abstract URL
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5. Adjuvant letrozole versus tamoxifen according to centrally-assessed ERBB2 status for postmenopausal women with endocrine-responsive early breast cancer: supplementary results from the BIG 1-98 randomised trial.

Author
Rasmussen BB; Regan MM; Lykkesfeldt AE; Dell'Orto P; Del Curto B; Henriksen KL; Mastropasqua MG; Price KN; Mery E; Lacroix-Triki M; Braye S; Altermatt HJ; Gelber RD; Castiglione-Gertsch M; Goldhirsch A; Gusterson BA; Thurlimann B; Coates AS; Viale G;
Institution
Department of Pathology, Nordsjaellands Hospital, Hilleroed, Denmark. bbr@noh.regionh.dk
Journal
Lancet Oncol. 2008 Jan;9(1):23-8. Epub 2007 Dec 20.
Abstract URL
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6. Late cardiac effects of adjuvant chemotherapy in breast cancer survivors treated on Southwest Oncology Group protocol s8897.

Author
Ganz PA; Hussey MA; Moinpour CM; Unger JM; Hutchins LF; Dakhil SR; Giguere JK; Goodwin JW; Martino S; Albain KS;
Institution
School of Medicine, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, 650 Charles Young Dr South, Room A2-125 CHS, Los Angeles, CA 90095-6900, USA. pganz@ucla.edu
Journal
J Clin Oncol. 2008 Mar 10;26(8):1223-30. Epub 2008 Jan 28.
Abstract URL
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7. A Randomized clinical trial on sentinel lymph node biopsy versus axillary lymph node dissection in breast cancer: results of the Sentinella/GIVOM trial.

Author
Zavagno G; De Salvo GL; Scalco G; Bozza F; Barutta L; Del Bianco P; Renier M; Racano C; Carraro P; Nitti D;
Institution
Clinica Chirurgica II, University of Padova, Italy. giorgio.zavagno@unipd.it
Journal
Ann Surg. 2008 Feb;247(2):207-13.
Abstract URL
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8. Phase II study of predictive biomarker profiles for response targeting human epidermal growth factor receptor 2 (HER-2) in advanced inflammatory breast cancer with lapatinib monotherapy.

Author
Johnston S; Trudeau M; Kaufman B; Boussen H; Blackwell K; LoRusso P; Lombardi DP; Ben Ahmed S; Citrin DL; DeSilvio ML; Harris J; Westlund RE; Salazar V; Zaks TZ; Spector NL;
Institution
Department of Medicine-Breast Unit, Royal Marsden Hospital, London, United Kingdom.
Journal
J Clin Oncol. 2008 Mar 1;26(7):1066-72. Epub 2008 Jan 22.
Abstract URL
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9. A phase I/II study of bortezomib and capecitabine in patients with metastatic breast cancer previously treated with taxanes and/or anthracyclines.

Author
Schmid P; Kuhnhardt D; Kiewe P; Lehenbauer-Dehm S; Schippinger W; Greil R; Lange W; Preiss J; Niederle N; Brossart P; Freier W; Kummel S; Van de Velde H; Regierer A; Possinger K;
Institution
Medical Oncology, Imperial College London, Charing Cross Hospital, London, UK. p.schmid@imperial.ac.uk
Journal
Ann Oncol. 2008 May;19(5):871-6. Epub 2008 Jan 21.
Abstract URL
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10. Gemcitabine plus capecitabine combination in metastatic breast cancer patients previously treated with anthracyclines and taxanes.

Author
Benekli M; Yildiz R; Uner A; Er O; Yamac D; Alkis N; Coskun U; Camci C; Buyukberber S;
Institution
Department of Medical Oncology, Erciyes University Faculty of Medicine, Kayseri, Turkey. mbenekli@gazi.edu.tr
Journal
Oncology. 2007;72(5-6):308-13. Epub 2008 Jan 14.
Abstract URL
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11. Predictors of contralateral prophylactic mastectomy in women with a BRCA1 or BRCA2 mutation: the Hereditary Breast Cancer Clinical Study Group.

Author
Metcalfe KA; Lubinski J; Ghadirian P; Lynch H; Kim-Sing C; Friedman E; Foulkes WD; Domchek S; Ainsworth P; Isaacs C; Tung N; Gronwald J; Cummings S; Wagner T; Manoukian S; Moller P; Weitzel J; Sun P; Narod SA;
Institution
Lawrence Bloomberg Faculty of Nursing, University of Toronto, Canada.
Journal
J Clin Oncol. 2008 Mar 1;26(7):1093-7. Epub 2008 Jan 14.
Abstract URL
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12. Information and decision making: patients' needs and experiences in the course of breast cancer treatment.

Author
Vogel BA; Bengel J; Helmes AW;
Institution
Department of Rehabilitation Psychology and Psychotherapy, University of Freiburg, Germany. vogel@psychologie.uni-freiburg.de
Journal
Patient Educ Couns. 2008 Apr;71(1):79-85. Epub 2008 Jan 8.
Abstract URL
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13. Dose-finding phase I and pharmacokinetic study of capecitabine (Xeloda) in combination with epirubicin and cyclophosphamide (CEX) in patients with inoperable or metastatic breast cancer.

Author
Saji S; Toi M; Morita S; Iwata H; Ito Y; Ohno S; Kobayashi T; Hozumi Y; Sakamoto J;
Institution
Department of Surgery and Breast Oncology, Division of Clinical Trials and Research, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan.
Journal
Oncology. 2007;72(5-6):330-7. Epub 2008 Jan 12.
Abstract URL
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14. The TARGIT trial: targeted intraoperative radiation therapy versus conventional postoperative whole-breast radiotherapy after breast-conserving surgery for the management of early-stage invasive breast cancer (a trial update).

Author
Holmes DR; Baum M; Joseph D;
Institution
American College of Surgeon, 55 East Erie Street, Chicago, IL 60611-2797, USA. dholmes@usc.edu
Journal
Am J Surg. 2007 Oct;194(4):507-10.
Abstract URL
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15. Five-year results: the initial clinical trial of MammoSite balloon brachytherapy for partial breast irradiation in early-stage breast cancer.

Author
Benitez PR; Keisch ME; Vicini F; Stolier A; Scroggins T; Walker A; White J; Hedberg P; Hebert M; Arthur D; Zannis V; Quiet C; Streeter O; Silverstein M;
Institution
Department of Surgery, William Beaumont Hospital, 3577 W. 13 Mile Rd, Suite 201, Beaumont Cancer Center, Royal Oak, MI 48073, USA. pbenitez@beaumont.edu
Journal
Am J Surg. 2007 Oct;194(4):456-62.
Abstract URL
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16. Survival in breast cancer after nipple-sparing subcutaneous mastectomy and immediate reconstruction with implants: a prospective trial with 13 years median follow-up in 216 patients.

Author
Benediktsson KP; Perbeck L;
Institution
Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Solna, 171 76 Stockholm, Sweden. krispetben@hotmail.com
Journal
Eur J Surg Oncol. 2008 Feb;34(2):143-8. Epub 2007 Aug 20.
Abstract URL
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17. Effects of supportive-expressive group therapy on survival of patients with metastatic breast cancer: a randomized prospective trial.

Author
Spiegel D; Butler LD; Giese-Davis J; Koopman C; Miller E; DiMiceli S; Classen CC; Fobair P; Carlson RW; Kraemer HC;
Institution
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305-5718, USA. dspiegel@stanford.edu
Journal
Cancer. 2007 Sep 1;110(5):1130-8.
Abstract URL
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18. Capecitabine and paclitaxel combination chemotherapy for inoperable or recurrent breast cancer: a phase I dose-finding study by the Kinki Breast Cancer Study Group.

Author
Masuda N; Taguchi T; Nakayama T; Shiba E; Watatani M; Kurebayashi J; Takatsuka Y; Sakamoto J; Noguchi S;
Institution
Department of Surgery, Breast Oncology Group, Osaka National Hospital, 2-1-14, Honenzaka, Chuou-ku, Osaka city, Osaka 540-0006, Japan. nmasuda@alpha.ocn.ne.jp
Journal
Cancer Chemother Pharmacol. 2008 May;61(6):989-95. Epub 2007 Jul 20.
Abstract URL
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19. Morbidity in breast cancer patients with sentinel node metastases undergoing delayed axillary lymph node dissection (ALND) compared with immediate ALND.

Author
Goyal A; Newcombe RG; Chhabra A; Mansel RE;
Institution
Department of Surgery, School of Medicine, Cardiff University, Cardiff, United Kingdom. goyala@cf.ac.uk
Journal
Ann Surg Oncol. 2008 Jan;15(1):262-7. Epub 2007 Sep 19.
Abstract URL
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20. Multi-institutional experience using the MammoSite radiation therapy system in the treatment of early-stage breast cancer: 2-year results.

Author
Cuttino LW; Keisch M; Jenrette JM; Dragun AE; Prestidge BR; Quiet CA; Vicini FA; Rescigno J; Wazer DE; Kaufman SA; Ramakrishnan VR; Patel R; Arthur DW;
Institution
Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298-0058, USA. lcuttino@mcvh-vcu.edu
Journal
Int J Radiat Oncol Biol Phys. 2008 May 1;71(1):107-14. Epub 2007 Nov 26.
Abstract URL
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21. Randomized trial of high-dose chemotherapy with autologous peripheral-blood stem-cell support compared with standard-dose chemotherapy in women with metastatic breast cancer: NCIC MA.16.

Author
Crump M; Gluck S; Tu D; Stewart D; Levine M; Kirkbride P; Dancey J; O'Reilly S; Shore T; Couban S; Girouard C; Marlin S; Shepherd L; Pritchard KI;
Institution
National Cancer Institute of Canada Clinical Trials Group, Kingston, Ontario, Canada. michael.crump@uhn.on.ca
Journal
J Clin Oncol. 2008 Jan 1;26(1):37-43. Epub 2007 Nov 19.
Abstract URL
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22. Survival outcome and cost-effectiveness with docetaxel and paclitaxel in patients with metastatic breast cancer: a population-based evaluation.

Author
Vu T; Ellard S; Speers CH; Taylor SC; de Lemos ML; Hu F; Kuik K; Olivotto IA; Vu T; Ellard S; Speers CH; Taylor SC; de Lemos ML; Hu F; Kuik K; Olivotto IA;
Institution
Provincial Systemic Therapy Program, BC Cancer Agency, Vancouver, British Columbia, Canada.
Journal
Ann Oncol. 2008 Mar;19(3):461-4. Epub 2007 Nov 15.
Abstract URL
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23. Phase III study to evaluate the use of high-dose chemotherapy as consolidation of treatment for high-risk postoperative breast cancer: Japan Clinical Oncology Group study, JCOG 9208.

Author
Tokuda Y; Tajima T; Narabayashi M; Takeyama K; Watanabe T; Fukutomi T; Chou T; Sano M; Igarashi T; Sasaki Y; Ogura M; Miura S; Okamoto S; Ogita M; Kasai M; Kobayashi T; Fukuda H; Takashima S; Tobinai K;
Institution
Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan. tokuda@is.icc.u-tokai.ac.jp
Journal
Cancer Sci. 2008 Jan;99(1):145-51. Epub 2007 Oct 25.
Abstract URL
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24. Adjuvant cyclic Tamoxifen and Megestrol acetate treatment in postmenopausal breast cancer patients--longterm follow-up.

Author
Fjosne HE; Jacobsen AB; Lundgren S;
Institution
Breast and Endocrine Unit, Department of Surgery, St. Olavs University Hospital, N-7006 Trondheim, Norway. hans.fjosne@stolav.no
Journal
Eur J Surg Oncol. 2008 Jan;34(1):6-12. Epub 2007 Sep 18.
Abstract URL
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25. Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women's Healthy Eating and Living (WHEL) randomized trial.

Author
Pierce JP; Natarajan L; Caan BJ; Parker BA; Greenberg ER; Flatt SW; Rock CL; Kealey S; Al-Delaimy WK; Bardwell WA; Carlson RW; Emond JA; Faerber S; Gold EB; Hajek RA; Hollenbach K; Jones LA; Karanja N; Madlensky L; Marshall J; Newman VA; Ritenbaugh C; Thomson CA; Wasserman L; Stefanick ML;
Institution
Moores UCSD Cancer Center, University of California, San Diego, La Jolla , CA 92093-0901, USA. jppierce@ucsd.edu
Journal
JAMA. 2007 Jul 18;298(3):289-98.
Abstract URL
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26. Adjuvant dose-dense sequential chemotherapy with epirubicin, CMF and weekly paclitaxel in patients with resected high-risk breast cancer: a Hellenic Cooperative Oncology Group (HeCOG) study.

Author
Papadimitriou CA; Papakostas P; Timotheadou E; Aravantinos G; Bamias A; Fountzilas G;
Institution
Department of Clinical Therapeutics, Alexandra Hospital, University of Athens School of Medicine, Athens, Greece.chr_papadim@yahoo.gr
Journal
Cancer Invest. 2008 Jun;26(5):491-8.
Abstract URL
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27. Capecitabine and vinorelbine as first-line treatment in elderly patients (> or =65 years) with metastatic breast cancer. A phase II trial (SAKK 25/99).

Author
Hess D; Koberle D; Thurlimann B; Pagani O; Schonenberger A; Mattmann S; Rochlitz C; Rauch D; Schuller JC; Ballabeni P; Ribi K;
Institution
Department of Internal Medicine, Division of Oncology-Hematology, Kantonsspital St. Gallen, St. Gallen, Switzerland. dagmar.hess@kssg.ch
Journal
Oncology. 2007;73(3-4):228-37. Epub 2008 Apr 17.
Abstract URL
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28. Phase II trial of pegylated liposomal doxorubicin-cyclophosphamide combination as first-line chemotherapy in older metastatic breast cancer patients.

Author
Kurtz JE; Rousseau F; Meyer N; Delozier T; Serin D; Nabet M; Djafari L; Dufour P;
Institution
Hopitaux Universitaires de Strasbourg, Strasbourg, France.
Journal
Oncology. 2007;73(3-4):210-4. Epub 2008 Apr 17.
Abstract URL
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29. Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer.

Author
Lin NU; Carey LA; Liu MC; Younger J; Come SE; Ewend M; Harris GJ; Bullitt E; Van den Abbeele AD; Henson JW; Li X; Gelman R; Burstein HJ; Kasparian E; Kirsch DG; Crawford A; Hochberg F; Winer EP;
Institution
Dana-Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA.
Journal
J Clin Oncol. 2008 Apr 20;26(12):1993-9.
Abstract URL
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30. Weekly paclitaxel in the adjuvant treatment of breast cancer.

Author
Sparano JA; Wang M; Martino S; Jones V; Perez EA; Saphner T; Wolff AC; Sledge GW Jr; Wood WC; Davidson NE;
Institution
Eastern Cooperative Oncology Group, Philadelphia, USA. jsparano@montefiore.org
Journal
N Engl J Med. 2008 Apr 17;358(16):1663-71.
Abstract URL
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31. Neoadjuvant vinorelbine-capecitabine versus docetaxel-doxorubicin-cyclophosphamide in early nonresponsive breast cancer: phase III randomized GeparTrio trial.

Author
von Minckwitz G; Kummel S; Vogel P; Hanusch C; Eidtmann H; Hilfrich J; Gerber B; Huober J; Costa SD; Jackisch C; Loibl S; Mehta K; Kaufmann M;
Institution
German Breast Group, Frankfurt, Germany. minckwitz@germanbreastgroup.de
Journal
J Natl Cancer Inst. 2008 Apr 16;100(8):542-51. Epub 2008 Apr 8.
Abstract URL
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32. Intensified neoadjuvant chemotherapy in early-responding breast cancer: phase III randomized GeparTrio study.

Author
von Minckwitz G; Kummel S; Vogel P; Hanusch C; Eidtmann H; Hilfrich J; Gerber B; Huober J; Costa SD; Jackisch C; Loibl S; Mehta K; Kaufmann M;
Institution
German Breast Group, Frankfurt, Germany. minckwitz@germanbreastgroup.de
Journal
J Natl Cancer Inst. 2008 Apr 16;100(8):552-62. Epub 2008 Apr 8.
Abstract URL
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33. Risedronate prevents bone loss in breast cancer survivors: a 2-year, randomized, double-blind, placebo-controlled clinical trial.

Author
Greenspan SL; Brufsky A; Lembersky BC; Bhattacharya R; Vujevich KT; Perera S; Sereika SM; Vogel VG;
Institution
Department of Medicine, University of Pittsburgh, 3471 Fifth Ave, Kaufmann Suite 1110, Pittsburgh, PA 15213, USA. greenspans@dom.pitt.edu
Journal
J Clin Oncol. 2008 Jun 1;26(16):2644-52. Epub 2008 Apr 21.
Abstract URL
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34. Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment.

Author
Thomas ES;
Institution
Journal
J Clin Oncol. 2008 May 1;26(13):2223.

35. Bortezomib/docetaxel combination therapy in patients with anthracycline-pretreated advanced/metastatic breast cancer: a phase I/II dose-escalation study.

Author
Awada A; Albanell J; Canney PA; Dirix LY; Gil T; Cardoso F; Gascon P; Piccart MJ; Baselga J;
Institution
Medical Oncology Clinic, Institut Jules Bordet, Brussels, Belgium. ahmad.awada@bordet.be
Journal
Br J Cancer. 2008 May 6;98(9):1500-7. Epub 2008 Apr 29.
Abstract URL
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36. Randomized phase 3 trial of fluorouracil, epirubicin, and cyclophosphamide alone or followed by Paclitaxel for early breast cancer.

Author
Martin M; Rodriguez-Lescure A; Ruiz A; Alba E; Calvo L; Ruiz-Borrego M; Munarriz B; Rodriguez CA; Crespo C; de Alava E; Lopez Garcia-Asenjo JA; Guitian MD; Almenar S; Gonzalez-Palacios JF; Vera F; Palacios J; Ramos M; Gracia Marco JM; Lluch A; Alvarez I; Segui MA; Mayordomo JI; Anton A; Baena JM; Plazaola A; Modolell A; Pelegri A; Mel JR; Aranda E; Adrover E; Alvarez JV; Garcia Puche JL; Sanchez-Rovira P; Gonzalez S; Lopez-Vega JM;
Institution
Servicio de Oncologia Medica, Hospital Universitario San Carlos, Ciudad Universitaria s/n, 28040 Madrid, Spain. mmartin@geicam.org
Journal
J Natl Cancer Inst. 2008 Jun 4;100(11):805-14. Epub 2008 May 27.
Abstract URL
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37. Neoadjuvant paclitaxel for operable breast cancer: multicenter phase II trial with clinical outcomes.

Author
Kimura M; Sano M; Fujimori M; Nakagomi H; Negishi T; Yanagita Y; Sato N;
Institution
Department of Surgery, General Ota Hospital, Ota, Gunma 373-8585, Japan. kimuraota@yahoo.co.jp
Journal
Anticancer Res. 2008 Mar-Apr;28(2B):1239-44.
Abstract URL
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38. Efficacy and safety of lapatinib as first-line therapy for ErbB2-amplified locally advanced or metastatic breast cancer.

Author
Gomez HL; Doval DC; Chavez MA; Ang PC; Aziz Z; Nag S; Ng C; Franco SX; Chow LW; Arbushites MC; Casey MA; Berger MS; Stein SH; Sledge GW;
Institution
Instituto Nacional de Enfermedades Neoplasicas, Hospital Alberto Sabogal, Lima, Peru. hgomez@inen.sld.pe
Journal
J Clin Oncol. 2008 Jun 20;26(18):2999-3005. Epub 2008 May 5.
Abstract URL
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39. Randomized phase III trial of weekly compared with every-3-weeks paclitaxel for metastatic breast cancer, with trastuzumab for all HER-2 overexpressors and random assignment to trastuzumab or not in HER-2 nonoverexpressors: final results of Cancer and Leukemia Group B protocol 9840.

Author
Seidman AD; Berry D; Cirrincione C; Harris L; Muss H; Marcom PK; Gipson G; Burstein H; Lake D; Shapiro CL; Ungaro P; Norton L; Winer E; Hudis C;
Institution
Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA. seidmana@mskcc.org
Journal
J Clin Oncol. 2008 Apr 1;26(10):1642-9.
Abstract URL
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40. Phase 3 study comparing the use of docetaxel on an every-3-week versus weekly schedule in the treatment of metastatic breast cancer.

Author
Rivera E; Mejia JA; Arun BK; Adinin RB; Walters RS; Brewster A; Broglio KR; Yin G; Esmaeli B; Hortobagyi GN; Valero V;
Institution
Department of Breast Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
Journal
Cancer. 2008 Apr 1;112(7):1455-61.
Abstract URL
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41. Interstitial laser thermotherapy (ILT) of breast cancer.

Author
Haraldsdottir KH; Ivarsson K; Gotberg S; Ingvar C; Stenram U; Tranberg KG;
Institution
Department of Surgery, Lund University Hospital, SE-22185 Lund, Sweden.
Journal
Eur J Surg Oncol. 2008 Jul;34(7):739-45. Epub 2008 Mar 4.
Abstract URL
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42. Changing indications for surgery in patients with stage IV breast cancer: a current perspective.

Author
Morrogh M; Park A; Norton L; King TA;
Institution
Breast Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
Journal
Cancer. 2008 Apr 1;112(7):1445-54.
Abstract URL
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43. Moderators of the effects of exercise training in breast cancer patients receiving chemotherapy: a randomized controlled trial.

Author
Courneya KS; McKenzie DC; Mackey JR; Gelmon K; Reid RD; Friedenreich CM; Ladha AB; Proulx C; Vallance JK; Lane K; Yasui Y; Segal RJ;
Institution
Faculty of Physical Education and Recreation, University of Alberta, Edmonton, Alberta, Canada. kerry.courneya@ualberta.ca
Journal
Cancer. 2008 Apr 15;112(8):1845-53.
Abstract URL
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44. Double-blind, randomized placebo controlled trial of fulvestrant compared with exemestane after prior nonsteroidal aromatase inhibitor therapy in postmenopausal women with hormone receptor-positive, advanced breast cancer: results from EFECT.

Author
Chia S; Gradishar W; Mauriac L; Bines J; Amant F; Federico M; Fein L; Romieu G; Buzdar A; Robertson JF; Brufsky A; Possinger K; Rennie P; Sapunar F; Lowe E; Piccart M;
Institution
Division of Medical Oncology, British Columbia Cancer Agency, University of British Columbia, 600 West 10 Avenue, Vancouver, BC, Canada. schia@bccancer.bc.ca
Journal
J Clin Oncol. 2008 Apr 1;26(10):1664-70. Epub 2008 Mar 3.
Abstract URL
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45. Long-term follow-up of acupuncture and hormone therapy on hot flushes in women with breast cancer: a prospective, randomized, controlled multicenter trial.

Author
Frisk J; Carlhall S; Kallstrom AC; Lindh-Astrand L; Malmstrom A; Hammar M;
Institution
Division of Obstetrics and Gynaecology, Department of Molecular and Clinical Medicine, Faculty of Health Sciences, University Hospital of Linkoping, Sweden.
Journal
Climacteric. 2008 Apr;11(2):166-74.
Abstract URL
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46. A randomized controlled trial of relaxation training to reduce hot flashes in women with primary breast cancer.

Author
Fenlon DR; Corner JL; Haviland JS;
Institution
School of Nursing & Midwifery, University of Southampton, Southampton, UK. dfenlon@soton.ac.uk <dfenlon@soton.ac.uk>
Journal
J Pain Symptom Manage. 2008 Apr;35(4):397-405.
Abstract URL
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47. Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane.

Author
Burstein HJ; Elias AD; Rugo HS; Cobleigh MA; Wolff AC; Eisenberg PD; Lehman M; Adams BJ; Bello CL; DePrimo SE; Baum CM; Miller KD;
Institution
Dana-Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA. hburstein@partners.org
Journal
J Clin Oncol. 2008 Apr 10;26(11):1810-6. Epub 2008 Mar 17.
Abstract URL
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48. Efficacy, toxicity, and quality of life in older women with early-stage breast cancer treated with letrozole or placebo after 5 years of tamoxifen: NCIC CTG intergroup trial MA.17.

Author
Muss HB; Tu D; Ingle JN; Martino S; Robert NJ; Pater JL; Whelan TJ; Palmer MJ; Piccart MJ; Shepherd LE; Pritchard KI; He Z; Goss PE;
Institution
University of Vermont College of Medicine, 1 South Prospect St, Saint Joseph 3400, Burlington, VT 05401, USA. hyman.muss@uvm.edu
Journal
J Clin Oncol. 2008 Apr 20;26(12):1956-64. Epub 2008 Mar 10.
Abstract URL
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49. Letrozole compared with tamoxifen for elderly patients with endocrine-responsive early breast cancer: the BIG 1-98 trial.

Author
Crivellari D; Sun Z; Coates AS; Price KN; Thurlimann B; Mouridsen H; Mauriac L; Forbes JF; Paridaens RJ; Castiglione-Gertsch M; Gelber RD; Colleoni M; Lang I; Del Mastro L; Gladieff L; Rabaglio M; Smith IE; Chirgwin JH; Goldhirsch A;
Institution
IBCSG Coordinating Center, Effingerstrasse 40, CH-3008 Bern, Switzerland. dcrivellari@cro.it
Journal
J Clin Oncol. 2008 Apr 20;26(12):1972-9. Epub 2008 Mar 10.
Abstract URL
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50. Treatment of advanced hormone-sensitive breast cancer in postmenopausal women with exemestane alone or in combination with celecoxib.

Author
Dirix LY; Ignacio J; Nag S; Bapsy P; Gomez H; Raghunadharao D; Paridaens R; Jones S; Falcon S; Carpentieri M; Abbattista A; Lobelle JP;
Institution
Medical Oncology Unit, Oncologisch Centrum Sint-Augustinus, Oosterveldlaan 24, 2610 Wilrijk, Belgium. luc.dirix@gvagroup.be
Journal
J Clin Oncol. 2008 Mar 10;26(8):1253-9.
Abstract URL
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51. Effect of once-weekly epoetin beta on survival in patients with metastatic breast cancer receiving anthracycline- and/or taxane-based chemotherapy: results of the Breast Cancer-Anemia and the Value of Erythropoietin (BRAVE) study.

Author
Aapro M; Leonard RC; Barnadas A; Marangolo M; Untch M; Malamos N; Mayordomo J; Reichert D; Pedrini JL; Ukarma L; Scherhag A; Burger HU;
Institution
Institut Multidisciplinaire d'Oncologie, Clinique de Genolier, 1 route du Muids, Genolier, Switzerland. maapro@genolier.net
Journal
J Clin Oncol. 2008 Feb 1;26(4):592-8.
Abstract URL
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52. A phase II study of second-line neoadjuvant chemotherapy with capecitabine and radiation therapy for anthracycline-resistant locally advanced breast cancer.

Author
Gaui Mde F; Amorim G; Arcuri RA; Pereira G; Moreira D; Djahjah C; Biasoli I; Spector N;
Institution
Oncology and Pathology Services, National Cancer Institute, Rio de Janeiro, Brazil. mfgaui@hotmail.com
Journal
Am J Clin Oncol. 2007 Feb;30(1):78-81.
Abstract URL
Click here to view abstract

53. Phase III trial of concurrent or sequential adjuvant chemoradiotherapy after conservative surgery for early-stage breast cancer: final results of the ARCOSEIN trial.

Author
Toledano A; Azria D; Garaud P; Fourquet A; Serin D; Bosset JF; Miny-Buffet J; Favre A; Le Floch O; Calais G;
Institution
Department of Radiation Oncology, Henry Kaplan, Hopital Bretonneau, Tours, France. alain.toledano@gmail.com
Journal
J Clin Oncol. 2007 Feb 1;25(4):405-10.
Abstract URL
Click here to view abstract

54. Randomized, double-blind, placebo-controlled crossover trials of venlafaxine for hot flashes after breast cancer.

Author
Carpenter JS; Storniolo AM; Johns S; Monahan PO; Azzouz F; Elam JL; Johnson CS; Shelton RC;
Institution
Indiana University, 1111 Middle Drive NU340D, Indianapolis, Indiana 46202, USA. carpentj@iupui.edu
Journal
Oncologist. 2007 Jan;12(1):124-35.
Abstract URL
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55. 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial.

Author
Smith I; Procter M; Gelber RD; Guillaume S; Feyereislova A; Dowsett M; Goldhirsch A; Untch M; Mariani G; Baselga J; Kaufmann M; Cameron D; Bell R; Bergh J; Coleman R; Wardley A; Harbeck N; Lopez RI; Mallmann P; Gelmon K; Wilcken N; Wist E; Sanchez Rovira P; Piccart-Gebhart MJ;
Institution
Royal Marsden Hospital, London, UK. ian.smith@rmh.nhs.uk
Journal
Lancet. 2007 Jan 6;369(9555):29-36.
Abstract URL
Click here to view abstract

56. Does patient satisfaction with breast reconstruction change over time? Two-year results of the Michigan Breast Reconstruction Outcomes Study.

Author
Alderman AK; Kuhn LE; Lowery JC; Wilkins EG;
Institution
Section of Plastic Surgery, Department of Surgery, The University of Michigan, Medical Center, Ann Arbor, MI 48109-0340, USA.
Journal
J Am Coll Surg. 2007 Jan;204(1):7-12. Epub 2006 Nov 16.
Abstract URL
Click here to view abstract

57. Venlafaxine is superior to clonidine as treatment of hot flashes in breast cancer patients--a double-blind, randomized study.

Author
Loibl S; Schwedler K; von Minckwitz G; Strohmeier R; Mehta K; Kaufmann M;
Institution
Department of Obstetrics and Gynecology, University Hospital Frankfurt am Main, Frankfurt am Main, Germany.
Journal
Ann Oncol. 2007 Jan 17;.
Abstract URL
Click here to view abstract

58. Depression and anxiety in women with breast cancer and their partners.

Author
Badger T; Segrin C; Dorros SM; Meek P; Lopez AM;
Institution
College of Nursing, Department of Communication, The University of Arizona, and Arizona Cancer Center, Arizona Health Science Center, Tucson 85721-0203, USA. Tbadger@nursing.arizona.edu
Journal
Nurs Res. 2007 Jan-Feb;56(1):44-53.
Abstract URL
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59. Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer.

Author
Lee KS; Chung HC; Im SA; Park YH; Kim CS; Kim SB; Rha SY; Lee MY; Ro J;
Institution
Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, 809 Madu-1-dong, Ilsan-gu, Goyang-si, Gyeonggi-do 410-769, Republic of Korea.
Journal
Breast Cancer Res Treat. 2008 Mar;108(2):241-50. Epub 2007 May 3.
Abstract URL
Click here to view abstract

60. A Phase II trial evaluating the palliative benefit of second-line oral ibandronate in breast cancer patients with either a skeletal related event (SRE) or progressive bone metastases (BM) despite standard bisphosphonate (BP) therapy.

Author
Clemons M; Dranitsaris G; Ooi W; Cole DE;
Institution
Division of Medical Oncology, Princess Margaret Hospital, Toronto, ON, Canada. mark.clemons@uhn.on.ca
Journal
Breast Cancer Res Treat. 2008 Mar;108(1):79-85. Epub 2007 May 2.
Abstract URL
Click here to view abstract

61. A Phase 2 study of perifosine in advanced or metastatic breast cancer.

Author
Leighl NB; Dent S; Clemons M; Vandenberg TA; Tozer R; Warr DG; Crump RM; Hedley D; Pond GR; Dancey JE; Moore MJ;
Institution
Medical Oncology, Princess Margaret Hospital/University Health Network, Toronto, ON, Canada. Natasha.Leighl@uhn.on.ca
Journal
Breast Cancer Res Treat. 2008 Mar;108(1):87-92. Epub 2007 Apr 26.
Abstract URL
Click here to view abstract

62. A phase II study of trastuzumab and capecitabine for patients with HER2-overexpressing metastatic breast cancer: Japan Breast Cancer Research Network (JBCRN) 00 Trial.

Author
Yamamoto D; Iwase S; Kitamura K; Odagiri H; Yamamoto C; Nagumo Y;
Institution
Department of Surgery, Kansai Medical University Hirakata Hospital, Hirakata, Osaka 573-1191, Japan. yamamotd@hirakata.kmu.ac.jp
Journal
Cancer Chemother Pharmacol. 2008 Mar;61(3):509-14. Epub 2007 May 22.
Abstract URL
Click here to view abstract

63. Cancer risk among Los Angeles women with cosmetic breast implants.

Author
Deapen DM; Hirsch EM; Brody GS;
Institution
Department of Preventive Medicine, Division of Plastic Surgery, and Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. ddeapen@usc.edu
Journal
Plast Reconstr Surg. 2007 Jun;119(7):1987-92.
Abstract URL
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64. Trastuzumab plus vinorelbine or taxane chemotherapy for HER2-overexpressing metastatic breast cancer: the trastuzumab and vinorelbine or taxane study.

Author
Burstein HJ; Keshaviah A; Baron AD; Hart RD; Lambert-Falls R; Marcom PK; Gelman R; Winer EP;
Institution
Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. hburstein@partners.org
Journal
Cancer. 2007 Sep 1;110(5):965-72.
Abstract URL
Click here to view abstract

65. Morbidity comparison of sentinel lymph node biopsy versus conventional axillary lymph node dissection for breast cancer patients: results of the sentinella-GIVOM Italian randomised clinical trial.

Author
Del Bianco P; Zavagno G; Burelli P; Scalco G; Barutta L; Carraro P; Pietrarota P; Meneghini G; Morbin T; Tacchetti G; Pecoraro P; Belardinelli V; De Salvo GL;
Institution
Clinical Trials and Biostatistics Unit, Istituto Oncologico Veneto - IRCCS, Via Gattamelata 64, Padova, Italy.
Journal
Eur J Surg Oncol. 2008 May;34(5):508-13. Epub 2007 Jul 5.
Abstract URL
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66. A phase-I study evaluating the combination of pegylated liposomal doxorubicin and paclitaxel as salvage chemotherapy in metastatic breast cancer previously treated with anthracycline.

Author
Hong RL; Lin CH; Chao TY; Kao WY; Wang CH; Hsieh RK; Hwang WS;
Institution
Department of Oncology, National Taiwan University Hospital, No 7, Chung-Shan South Rd, Taipei 10016, Taiwan. rlhong@ha.mc.ntu.edu.tw
Journal
Cancer Chemother Pharmacol. 2008 Apr;61(5):847-53. Epub 2007 Jul 4.
Abstract URL
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67. Phase 2 randomized trial of primary endocrine therapy versus chemotherapy in postmenopausal patients with estrogen receptor-positive breast cancer.

Author
Semiglazov VF; Semiglazov VV; Dashyan GA; Ziltsova EK; Ivanov VG; Bozhok AA; Melnikova OA; Paltuev RM; Kletzel A; Berstein LM;
Institution
N. N. Petrov Research Institute of Oncology, St. Petersburg, Russia. ssemiglazov@mail.ru
Journal
Cancer. 2007 Jul 15;110(2):244-54.
Abstract URL
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68. Phase III randomized multicenter study on the effects of adjuvant CMF in patients with node-negative, rapidly proliferating breast cancer: twelve-year results and retrospective subgroup analysis.

Author
Amadori D; Nanni O; Volpi A; Casadei Giunchi D; Marangolo M; Livi L; Ravaioli A; Rossi AP; Gambi A; Luzi Fedeli S; Perroni D; Scarpi E; Becciolini A; Silvestrini R;
Institution
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Via Maroncelli 34/36, 47014 Meldola, Italy. segronco@ausl.fo.it
Journal
Breast Cancer Res Treat. 2008 Mar;108(2):259-64. Epub 2007 May 26.
Abstract URL
Click here to view abstract

69. Effects of a combined aerobic and resistance exercise program in breast cancer survivors: a randomized controlled trial.

Author
Milne HM; Wallman KE; Gordon S; Courneya KS;
Institution
School of Human Movement and Exercise Science, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia. helenmilne@ekit.com
Journal
Breast Cancer Res Treat. 2008 Mar;108(2):279-88. Epub 2007 May 26.
Abstract URL
Click here to view abstract

70. Morbidity of sentinel lymph node biopsy (SLN) alone versus SLN and completion axillary lymph node dissection after breast cancer surgery: a prospective Swiss multicenter study on 659 patients.

Author
Langer I; Guller U; Berclaz G; Koechli OR; Schaer G; Fehr MK; Hess T; Oertli D; Bronz L; Schnarwyler B; Wight E; Uehlinger U; Infanger E; Burger D; Zuber M; Langer I; Guller U; Berclaz G; Koechli OR; Schaer G; Fehr MK; Hess T; Oertli D; Bronz L; Schnarwyler B; Wight E; Uehlinger U; Infanger E; Burger D; Zuber M;
Institution
Department of Surgery, University Hospital Basel, Basel, Switzerland.
Journal
Ann Surg. 2007 Mar;245(3):452-61.
Abstract URL
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71. Elevated plasma tissue inhibitor of metalloproteinase-1 level predicts decreased response and survival in metastatic breast cancer.

Author
Lipton A; Ali SM; Leitzel K; Demers L; Evans DB; Hamer P; Brown-Shimer S; Pierce K; Carney W;
Institution
Department of Hematology-Oncology, Penn State University, Milton S. Hershey Medical Center, Hershey, Pennsylvania 17033, USA.
Journal
Cancer. 2007 May 15;109(10):1933-9.
Abstract URL
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72. Randomized controlled trial comparing a low-fat diet with a weight-reduction diet in breast cancer-related lymphedema.

Author
Shaw C; Mortimer P; Judd PA; Shaw C; Mortimer P; Judd PA;
Institution
Royal Marsden NHS Foundation Trust, London, UK. clare.shaw@rmh.nhs.uk
Journal
Cancer. 2007 May 15;109(10):1949-56.
Abstract URL
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73. Benefits of supervised group exercise programme for women being treated for early stage breast cancer: pragmatic randomised controlled trial.

Author
Mutrie N; Campbell AM; Whyte F; McConnachie A; Emslie C; Lee L; Kearney N; Walker A; Ritchie D;
Institution
Department of Sport, Culture and the Arts, Strathclyde University, Glasgow G13 1PP. nanette.mutrie@strath.ac.uk
Journal
BMJ. 2007 Mar 10;334(7592):517. Epub 2007 Feb 16.
Abstract URL
Click here to view abstract

74. Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup Exemestane Study): a randomised controlled trial.

Author
Coombes RC; Kilburn LS; Snowdon CF; Paridaens R; Coleman RE; Jones SE; Jassem J; Van de Velde CJ; Delozier T; Alvarez I; Del Mastro L; Ortmann O; Diedrich K; Coates AS; Bajetta E; Holmberg SB; Dodwell D; Mickiewicz E; Andersen J; Lonning PE; Cocconi G; Forbes J; Castiglione M; Stuart N; Stewart A; Fallowfield LJ; Bertelli G; Hall E; Bogle RG; Carpentieri M; Colajori E; Subar M; Ireland E; Bliss JM;
Institution
Cancer Research UK Department of Cancer Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Imperial College London, Faculty of Medicine, Hammersmith Hospitals Trust, London W12 0NN, UK.
Journal
Lancet. 2007 Feb 17;369(9561):559-70.
Abstract URL
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75. Phase II Study of Neoadjuvant Docetaxel, Vinorelbine, and Trastuzumab Followed by Surgery and Adjuvant Doxorubicin Plus Cyclophosphamide in Women With Human Epidermal Growth Factor Receptor 2-Overexpressing Locally Advanced Breast Cancer.

Author
Limentani SA; Brufsky AM; Erban JK; Jahanzeb M; Lewis D;
Institution
Carolinas Hematology-Oncology Associates; The Blumenthal Cancer Center, Charlotte, NC; Department of Medicine, Division of Hematology-Oncology, University of Pittsburgh Magee-Womens Hospital, Pittsburgh, PA; Department of Medicine, Tufts-New England Medical Center, Boston, MA; and Division of Hematology-Oncology, University of Tennessee College of Medicine, Memphis, TN.
Journal
J Clin Oncol. 2007 Feb 12;.
Abstract URL
Click here to view abstract