Saturday, September 6, 2008 - 11:08PM EST

Clinical Trials

1. Dose-escalation of filgrastim does not improve efficacy: clinical tolerability and long-term follow-up on CALGB study 9141 adjuvant chemotherapy for node-positive breast cancer patients using dose-intensified doxorubicin plus cyclophosphamide followed by paclitaxel.

Author
Liu MC; Demetri GD; Berry DA; Norton L; Broadwater G; Robert NJ; Duggan D; Hayes DF; Henderson IC; Lyss A; Hopkins J; Kaufman PA; Marcom PK; Younger J; Lin N; Tkaczuk K; Winer EP; Hudis CA;
Institution
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3800 Reservoir Road NW, Washington, DC 20007-2198, USA. liumc@georgetown.edu
Journal
Cancer Treat Rev. 2008 May;34(3):223-30. Epub 2008 Jan 30.
Abstract URL
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2. Weekly docetaxel versus CMF as adjuvant chemotherapy for elderly breast cancer patients: safety data from the multicentre phase 3 randomised ELDA trial.

Author
Nuzzo F; Morabito A; De Maio E; Di Rella F; Gravina A; Labonia V; Landi G; Pacilio C; Piccirillo MC; Rossi E; D'Aiuto G; Thomas R; Gori S; Colozza M; De Placido S; Lauria R; Signoriello G; Gallo C; Perrone F; de Matteis A;
Institution
National Cancer Institute, Naples, Italy.
Journal
Crit Rev Oncol Hematol. 2008 May;66(2):171-80. Epub 2007 Dec 21.
Abstract URL
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3. Survival after adjuvant oophorectomy and tamoxifen in operable breast cancer in premenopausal women.

Author
Love RR; Van Dinh N; Quy TT; Linh ND; Tung ND; Shen TZ; Hade EM; Young GS; Jarjoura D;
Institution
Ohio State University, B402 Starling Loving Hall, 320 W 10th Ave, Columbus, OH 43210, USA. Richard.Love@osumc.edu
Journal
J Clin Oncol. 2008 Jan 10;26(2):253-7. Epub 2007 Dec 17.
Abstract URL
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4. Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial.

Author
Forbes JF; Cuzick J; Buzdar A; Howell A; Tobias JS; Baum M;
Institution
Journal
Lancet Oncol. 2008 Jan;9(1):45-53.
Abstract URL
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5. Adjuvant letrozole versus tamoxifen according to centrally-assessed ERBB2 status for postmenopausal women with endocrine-responsive early breast cancer: supplementary results from the BIG 1-98 randomised trial.

Author
Rasmussen BB; Regan MM; Lykkesfeldt AE; Dell'Orto P; Del Curto B; Henriksen KL; Mastropasqua MG; Price KN; Mery E; Lacroix-Triki M; Braye S; Altermatt HJ; Gelber RD; Castiglione-Gertsch M; Goldhirsch A; Gusterson BA; Thurlimann B; Coates AS; Viale G;
Institution
Department of Pathology, Nordsjaellands Hospital, Hilleroed, Denmark. bbr@noh.regionh.dk
Journal
Lancet Oncol. 2008 Jan;9(1):23-8. Epub 2007 Dec 20.
Abstract URL
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6. Late cardiac effects of adjuvant chemotherapy in breast cancer survivors treated on Southwest Oncology Group protocol s8897.

Author
Ganz PA; Hussey MA; Moinpour CM; Unger JM; Hutchins LF; Dakhil SR; Giguere JK; Goodwin JW; Martino S; Albain KS;
Institution
School of Medicine, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, 650 Charles Young Dr South, Room A2-125 CHS, Los Angeles, CA 90095-6900, USA. pganz@ucla.edu
Journal
J Clin Oncol. 2008 Mar 10;26(8):1223-30. Epub 2008 Jan 28.
Abstract URL
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7. A Randomized clinical trial on sentinel lymph node biopsy versus axillary lymph node dissection in breast cancer: results of the Sentinella/GIVOM trial.

Author
Zavagno G; De Salvo GL; Scalco G; Bozza F; Barutta L; Del Bianco P; Renier M; Racano C; Carraro P; Nitti D;
Institution
Clinica Chirurgica II, University of Padova, Italy. giorgio.zavagno@unipd.it
Journal
Ann Surg. 2008 Feb;247(2):207-13.
Abstract URL
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8. Phase II study of predictive biomarker profiles for response targeting human epidermal growth factor receptor 2 (HER-2) in advanced inflammatory breast cancer with lapatinib monotherapy.

Author
Johnston S; Trudeau M; Kaufman B; Boussen H; Blackwell K; LoRusso P; Lombardi DP; Ben Ahmed S; Citrin DL; DeSilvio ML; Harris J; Westlund RE; Salazar V; Zaks TZ; Spector NL;
Institution
Department of Medicine-Breast Unit, Royal Marsden Hospital, London, United Kingdom.
Journal
J Clin Oncol. 2008 Mar 1;26(7):1066-72. Epub 2008 Jan 22.
Abstract URL
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9. A phase I/II study of bortezomib and capecitabine in patients with metastatic breast cancer previously treated with taxanes and/or anthracyclines.

Author
Schmid P; Kuhnhardt D; Kiewe P; Lehenbauer-Dehm S; Schippinger W; Greil R; Lange W; Preiss J; Niederle N; Brossart P; Freier W; Kummel S; Van de Velde H; Regierer A; Possinger K;
Institution
Medical Oncology, Imperial College London, Charing Cross Hospital, London, UK. p.schmid@imperial.ac.uk
Journal
Ann Oncol. 2008 May;19(5):871-6. Epub 2008 Jan 21.
Abstract URL
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10. Gemcitabine plus capecitabine combination in metastatic breast cancer patients previously treated with anthracyclines and taxanes.

Author
Benekli M; Yildiz R; Uner A; Er O; Yamac D; Alkis N; Coskun U; Camci C; Buyukberber S;
Institution
Department of Medical Oncology, Erciyes University Faculty of Medicine, Kayseri, Turkey. mbenekli@gazi.edu.tr
Journal
Oncology. 2007;72(5-6):308-13. Epub 2008 Jan 14.
Abstract URL
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