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Chronic Obstructive Pulmonary Disease > What Your Doctor is Reading About Chronic Obstructive Pulmonary Disease > Clinical Trials

Clinical Trials

1. The psychologic consequences of chronic dyspnea in chronic pulmonary obstruction disease: the effects of acupressure on depression.

Author: Wu HS; Lin LC; Wu SC; Lin JG;
Institution: School of Nursing, National Yang-Ming University, Taipei, Taiwan.
Journal: J Altern Complement Med. 2007 Mar;13(2):253-61.
Abstract URL: Click here to view abstract

2. Pulmonary embolism and deep venous thrombosis in hospitalized adults with chronic obstructive pulmonary disease.

Author: Stein PD; Beemath A; Meyers FA; Olson RE;
Institution: St Joseph Mercy Oakland Hospital, Pontiac 48341-5023, and Wayne State University, Detroit, Michigan, USA. steinp@trinity-health.org
Journal: J Cardiovasc Med (Hagerstown). 2007 Apr;8(4):253-7.
Abstract URL: Click here to view abstract

3. The traditional herbal medicine Hochuekkito improves systemic inflammation in patients with chronic obstructive pulmonary disease.

Author: Shinozuka N; Tatsumi K; Nakamura A; Terada J; Kuriyama T;
Institution
Journal: J Am Geriatr Soc. 2007 Feb;55(2):313-4.

4. Screening of cognitive impairment in chronic obstructive pulmonary disease.

Author: Antonelli-Incalzi R; Corsonello A; Trojano L; Pedone C; Acanfora D; Spada A; Izzo O; Rengo F;
Institution: Department of Geriatric Medicine, University Campus Bio-Medico, Rome, Italy.
Journal: Dement Geriatr Cogn Disord. 2007;23(4):264-70. Epub 2007 Mar 12.
Abstract URL: Click here to view abstract

5. Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy.

Author: Stolz D; Christ-Crain M; Bingisser R; Leuppi J; Miedinger D; Muller C; Huber P; Muller B; Tamm M;
Institution: Clinics of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Basel, Switzerland. dstolz@uhbs.ch
Journal: Chest. 2007 Jan;131(1):9-19.
Abstract URL: Click here to view abstract

6. Pulmonary rehabilitation improves depression, anxiety, dyspnea and health status in patients with COPD.

Author: Paz-Diaz H; Montes de Oca M; Lopez JM; Celli BR;
Institution: Pulmonary Division, Hospital Universitario de Caracas, Universidad Central de Venezuela, Caracas, Venezuela.
Journal: Am J Phys Med Rehabil. 2007 Jan;86(1):30-6.
Abstract URL: Click here to view abstract

7. Depressive symptoms and chronic obstructive pulmonary disease: effect on mortality, hospital readmission, symptom burden, functional status, and quality of life.

Author: Ng TP; Niti M; Tan WC; Cao Z; Ong KC; Eng P;
Institution: Gerontological Research Programme, Faculty of Medicine, National University of Singapore, Singapore. pcmngtp@nus.edu.sg
Journal: Arch Intern Med. 2007 Jan 8;167(1):60-7.
Abstract URL: Click here to view abstract

8. Impact of salmeterol/fluticasone propionate versus salmeterol on exacerbations in severe chronic obstructive pulmonary disease.

Author: Kardos P; Wencker M; Glaab T; Vogelmeier C;
Institution: Group Practice and Center for Respiratory and Sleep Medicine, Allergy, Maingau Hospital, Scheffelstrasse 2, 60318 Frankfurt am Main, Germany. pkardos@aol.com
Journal: Am J Respir Crit Care Med. 2007 Jan 15;175(2):144-9. Epub 2006 Oct 19.
Abstract URL: Click here to view abstract

9. Improving outcomes for COPD patients with mild-to-moderate anxiety and depression: a systematic review of cognitive behavioural therapy.

Author: Coventry PA; Gellatly JL; Coventry PA; Gellatly JL; Coventry PA; Gellatly JL;
Institution: School of Nursing, Midwifery and Social Work, The University of Manchester, UK. peter.a.coventry@manchester.ac.uk
Journal: Br J Health Psychol. 2008 Sep;13(Pt 3):381-400. Epub 2007 Apr 18.
Abstract URL: Click here to view abstract

10. Responses to tiotropium in African-American and Caucasian patients with chronic obstructive pulmonary disease.

Author: Rice KL; Leimer I; Kesten S; Niewoehner DE; Rice KL; Leimer I; Kesten S; Niewoehner DE; Rice KL; Leimer I; Kesten S; Niewoehner DE;
Institution: Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA. Kathryn.Rice@va.gov
Journal: Transl Res. 2008 Aug;152(2):88-94. Epub 2008 Jun 23.
Abstract URL: Click here to view abstract

11. Effect of salmeterol/fluticasone propionate on airway inflammation in COPD: a randomised controlled trial.

Author: Bourbeau J; Christodoulopoulos P; Maltais F; Yamauchi Y; Olivenstein R; Hamid Q; Bourbeau J; Christodoulopoulos P; Maltais F; Yamauchi Y; Olivenstein R; Hamid Q; Bourbeau J; Christodoulopoulos P; Maltais F; Yamauchi Y; Olivenstein R; Hamid Q;
Institution: Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University Health Centre, Montreal, Quebec, Canada.
Journal: Thorax. 2007 Nov;62(11):938-43. Epub 2007 Jun 8.
Abstract URL: Click here to view abstract

12. A double-blind crossover study comparing the safety and efficacy of three weeks of Flu/Sal 250/50 bid plus albuterol 180 ug prn q4 hours to Flu/Sal 250/50 bid plus albuterol/Ipratropium bromide 2 puffs prn q4 hours in patients with chronic obstructive pulmonary disease.

Author: Balkissoon R; Make B; Balkissoon R; Make B; Balkissoon R; Make B;
Institution: National Jewish Medical and Research Center, Denver, Colorado 80206, USA. balkissoonr@njc.org
Journal: COPD. 2008 Aug;5(4):221-7.
Abstract URL: Click here to view abstract

13. Are patients with COPD more active after pulmonary rehabilitation?

Author: Pitta F; Troosters T; Probst VS; Langer D; Decramer M; Gosselink R; Pitta F; Troosters T; Probst VS; Langer D; Decramer M; Gosselink R; Pitta F; Troosters T; Probst VS; Langer D; Decramer M; Gosselink R;
Institution: Respiratory Rehabilitation and Respiratory Division, University Hospital Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium.
Journal: Chest. 2008 Aug;134(2):273-80. Epub 2008 Apr 10.
Abstract URL: Click here to view abstract

14. Comparison of a combination of tiotropium plus formoterol to salmeterol plus fluticasone in moderate COPD.

Author: Rabe KF; Timmer W; Sagkriotis A; Viel K; Rabe KF; Timmer W; Sagkriotis A; Viel K; Rabe KF; Timmer W; Sagkriotis A; Viel K;
Institution: Department of Pulmonology C3-P, Leiden University Medical Center, Albinus-dreef 2 Postbus, NL-2300 Leiden, the Netherlands. k.f.rabe@lumc.nl
Journal: Chest. 2008 Aug;134(2):255-62. Epub 2008 Apr 10.
Abstract URL: Click here to view abstract

15. Randomized controlled trial of dietary creatine as an adjunct therapy to physical training in chronic obstructive pulmonary disease.

Author: Deacon SJ; Vincent EE; Greenhaff PL; Fox J; Steiner MC; Singh SJ; Morgan MD; Deacon SJ; Vincent EE; Greenhaff PL; Fox J; Steiner MC; Singh SJ; Morgan MD; Deacon SJ; Vincent EE; Greenhaff PL; Fox J; Steiner MC; Singh SJ; Morgan MD;
Institution: Institute for Lung Health, Department of Respiratory Medicine, Allergy and Thoracic Surgery, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester LE39QP, UK. sarah.deacon@uhl-tr.nhs.uk
Journal: Am J Respir Crit Care Med. 2008 Aug 1;178(3):233-9. Epub 2008 Apr 17.
Abstract URL: Click here to view abstract

16. Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study.

Author: Celli BR; Thomas NE; Anderson JA; Ferguson GT; Jenkins CR; Jones PW; Vestbo J; Knobil K; Yates JC; Calverley PM; Celli BR; Thomas NE; Anderson JA; Ferguson GT; Jenkins CR; Jones PW; Vestbo J; Knobil K; Yates JC; Calverley PM; Celli BR; Thomas NE; Anderson JA; Ferguson GT; Jenkins CR; Jones PW; Vestbo J; Knobil K; Yates JC; Calverley PM;
Institution: Tufts University School of Medicine, Pulmonary and Critical Care Division, Caritas-St Elizabeth's Medical Center, Boston, MA 02135-2997, USA. bcelli@copdnet.org
Journal: Am J Respir Crit Care Med. 2008 Aug 15;178(4):332-8. Epub 2008 May 29.
Abstract URL: Click here to view abstract

17. Oral or IV prednisolone in the treatment of COPD exacerbations: a randomized, controlled, double-blind study.

Author: de Jong YP; Uil SM; Grotjohan HP; Postma DS; Kerstjens HA; van den Berg JW; de Jong YP; Uil SM; Grotjohan HP; Postma DS; Kerstjens HA; van den Berg JW; de Jong YP; Uil SM; Grotjohan HP; Postma DS; Kerstjens HA; van den Berg JW;
Institution: Department of Pulmonology, Isala klinieken, Pulmonology, PO Box 10500, Zwolle 8000 GM, the Netherlands. y.p.de.jong@isala.nl
Journal: Chest. 2007 Dec;132(6):1741-7. Epub 2007 Jul 23.
Abstract URL: Click here to view abstract

18. Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): a randomised placebo-controlled study.

Author: Zheng JP; Kang J; Huang SG; Chen P; Yao WZ; Yang L; Bai CX; Wang CZ; Wang C; Chen BY; Shi Y; Liu CT; Chen P; Li Q; Wang ZS; Huang YJ; Luo ZY; Chen FP; Yuan JZ; Yuan BT; Qian HP; Zhi RC; Zhong NS; Zheng JP; Kang J; Huang SG; Chen P; Yao WZ; Yang L; Bai CX; Wang CZ; Wang C; Chen BY; Shi Y; Liu CT; Chen P; Li Q; Wang ZS; Huang YJ; Luo ZY; Chen FP; Yuan JZ; Yuan BT; Qian HP; Zhi RC; Zhong NS; Zheng JP; Kang J; Huang SG; Chen P; Yao WZ; Yang L; Bai CX; Wang CZ; Wang C; Chen BY; Shi Y; Liu CT; Chen P; Li Q; Wang ZS; Huang YJ; Luo ZY; Chen FP; Yuan JZ; Yuan BT; Qian HP; Zhi RC; Zhong NS;
Institution: Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical College, Guangzhou, China.
Journal: Lancet. 2008 Jun 14;371(9629):2013-8.
Abstract URL: Click here to view abstract

19. Safety of regadenoson, a selective adenosine A2A agonist, in patients with chronic obstructive pulmonary disease: A randomized, double-blind, placebo-controlled trial (RegCOPD trial).

Author: Thomas GS; Tammelin BR; Schiffman GL; Marquez R; Rice DL; Milikien D; Mathur V; Thomas GS; Tammelin BR; Schiffman GL; Marquez R; Rice DL; Milikien D; Mathur V; Thomas GS; Tammelin BR; Schiffman GL; Marquez R; Rice DL; Milikien D; Mathur V;
Institution: Cardiology Division, University of California, Irvine, Irvine, USA. gthomas@mimg.com
Journal: J Nucl Cardiol. 2008 May-Jun;15(3):319-28. Epub 2008 Apr 14.
Abstract URL: Click here to view abstract

20. Inspiratory muscle training in pulmonary rehabilitation program in COPD patients.

Author: Magadle R; McConnell AK; Beckerman M; Weiner P; Magadle R; McConnell AK; Beckerman M; Weiner P; Magadle R; McConnell AK; Beckerman M; Weiner P;
Institution: Department of Medicine A, Hillel Yaffe Medical Center, Hadera 38100, Israel.
Journal: Respir Med. 2007 Jul;101(7):1500-5. Epub 2007 Feb 27.
Abstract URL: Click here to view abstract

21. Effect of lung volume reduction surgery on resting pulmonary hemodynamics in severe emphysema.

Author: Criner GJ; Scharf SM; Falk JA; Gaughan JP; Sternberg AL; Patel NB; Fessler HE; Minai OA; Fishman AP; Criner GJ; Scharf SM; Falk JA; Gaughan JP; Sternberg AL; Patel NB; Fessler HE; Minai OA; Fishman AP; Criner GJ; Scharf SM; Falk JA; Gaughan JP; Sternberg AL; Patel NB; Fessler HE; Minai OA; Fishman AP; Criner GJ; Scharf SM; Falk JA; Gaughan JP; Sternberg AL; Patel NB; Fessler HE; Minai OA; Fishman AP;
Institution: Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA. crinerg@tuhs.temple.edu
Journal: Am J Respir Crit Care Med. 2007 Aug 1;176(3):253-60. Epub 2007 May 11.
Abstract URL: Click here to view abstract

22. Levofloxacin 500 mg once daily versus cefuroxime 250 mg twice daily in patients with acute exacerbations of chronic obstructive bronchitis: clinical efficacy and exacerbation-free interval.

Author: Petitpretz P; Chone C; Tremolieres F; Petitpretz P; Chone C; Tremolieres F; Petitpretz P; Chone C; Tremolieres F;
Institution: Hopital Andre Mignot, Le Chesnay, France. ppetitpretz@ch-versailles.fr
Journal: Int J Antimicrob Agents. 2007 Jul;30(1):52-9. Epub 2007 May 18.
Abstract URL: Click here to view abstract

23. Survival after lung volume reduction in chronic obstructive pulmonary disease: insights from small airway pathology.

Author: Hogg JC; Chu FS; Tan WC; Sin DD; Patel SA; Pare PD; Martinez FJ; Rogers RM; Make BJ; Criner GJ; Cherniack RM; Sharafkhaneh A; Luketich JD; Coxson HO; Elliott WM; Sciurba FC; Hogg JC; Chu FS; Tan WC; Sin DD; Patel SA; Pare PD; Martinez FJ; Rogers RM; Make BJ; Criner GJ; Cherniack RM; Sharafkhaneh A; Luketich JD; Coxson HO; Elliott WM; Sciurba FC; Hogg JC; Chu FS; Tan WC; Sin DD; Patel SA; Pare PD; Martinez FJ; Rogers RM; Make BJ; Criner GJ; Cherniack RM; Sharafkhaneh A; Luketich JD; Coxson HO; Elliott WM; Sciurba FC;
Institution: University of British Columbia iCAPTURE Centre for Cardiovascular and Pulmonary Research, St. Paul's Hospital, Vancouver, BC, Canada. jhogg@mrl.ubc.ca
Journal: Am J Respir Crit Care Med. 2007 Sep 1;176(5):454-9. Epub 2007 Jun 7.
Abstract URL: Click here to view abstract

24. A practical screening tool for anxiety and depression in patients with chronic breathing disorders.

Author: Kunik ME; Azzam PN; Souchek J; Cully JA; Wray NP; Krishnan LL; Nelson HA; Stanley MA;
Institution: Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, Michael E DeBakey Veteran Affairs Medical Center (152), 2002 Holcombe, Houston, TX 77030, USA. mkunik@bcm.tmc.edu
Journal: Psychosomatics. 2007 Jan-Feb;48(1):16-21.
Abstract URL: Click here to view abstract

25. Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trial.

Author: Aaron SD; Vandemheen KL; Fergusson D; Maltais F; Bourbeau J; Goldstein R; Balter M; O'Donnell D; McIvor A; Sharma S; Bishop G; Anthony J; Cowie R; Field S; Hirsch A; Hernandez P; Rivington R; Road J; Hoffstein V; Hodder R; Marciniuk D; McCormack D; Fox G; Cox G; Prins HB; Ford G; Bleskie D; Doucette S; Mayers I; Chapman K; Zamel N; FitzGerald M;
Institution: The Ottawa Health Research Institute and University of Ottawa, Ottawa, Ontario, Canada.
Journal: Ann Intern Med. 2007 Apr 17;146(8):545-55. Epub 2007 Feb 19.
Abstract URL: Click here to view abstract

26. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease.

Author: Calverley PM; Anderson JA; Celli B; Ferguson GT; Jenkins C; Jones PW; Yates JC; Vestbo J;
Institution: University Hospital Aintree, Liverpool, United Kingdom. pmacal@liverpool.ac.uk
Journal: N Engl J Med. 2007 Feb 22;356(8):775-89.
Abstract URL: Click here to view abstract

27. Impact of chronic obstructive pulmonary disease on post-myocardial infarction outcomes.

Author: Salisbury AC; Reid KJ; Spertus JA;
Institution: Mayo Graduate School of Medicine, Rochester, Minnesota, USA.
Journal: Am J Cardiol. 2007 Mar 1;99(5):636-41. Epub 2007 Jan 9.
Abstract URL: Click here to view abstract

28. Impact of COPD exacerbations on patient-centered outcomes.

Author: Cote CG; Dordelly LJ; Celli BR;
Institution: Bay Pines Veterans Affairs Health Care System, Respiratory Disease Section 111A, 10,000 Bay Pines Blvd, Bay Pines, FL 33744, USA. Claudia.cote@med.va.gov
Journal: Chest. 2007 Mar;131(3):696-704.
Abstract URL: Click here to view abstract

29. A randomized, placebo-controlled trial of bronchodilators for bronchoscopy in patients with COPD.

Author: Stolz D; Pollak V; Chhajed PN; Gysin C; Pflimlin E; Tamm M;
Institution: Department of Pulmonary, Allergy and Critical Care Medicine, University of Massachusetts Memorial Hospital, 55 Lake Ave N, Worcester, MA 01655, USA. stolzd@ummhc.org
Journal: Chest. 2007 Mar;131(3):765-72.
Abstract URL: Click here to view abstract

30. The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide.

Author: Wedzicha JA; Calverley PM; Seemungal TA; Hagan G; Ansari Z; Stockley RA; Wedzicha JA; Calverley PM; Seemungal TA; Hagan G; Ansari Z; Stockley RA; Wedzicha JA; Calverley PM; Seemungal TA; Hagan G; Ansari Z; Stockley RA;
Institution: Academic Unit of Respiratory Medicine, Royal Free & University College Medical School, University College London, London, UK. j.a.wedzicha@medsch.ucl.ac.uk
Journal: Am J Respir Crit Care Med. 2008 Jan 1;177(1):19-26. Epub 2007 Oct 4.
Abstract URL: Click here to view abstract

31. The effect of lung volume reduction surgery on chronic obstructive pulmonary disease exacerbations.

Author: Washko GR; Fan VS; Ramsey SD; Mohsenifar Z; Martinez F; Make BJ; Sciurba FC; Criner GJ; Minai O; Decamp MM; Reilly JJ; Washko GR; Fan VS; Ramsey SD; Mohsenifar Z; Martinez F; Make BJ; Sciurba FC; Criner GJ; Minai O; Decamp MM; Reilly JJ; Washko GR; Fan VS; Ramsey SD; Mohsenifar Z; Martinez F; Make BJ; Sciurba FC; Criner GJ; Minai O; Decamp MM; Reilly JJ;
Institution: Pulmonary and Critical Care Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. gwashko@partners.org
Journal: Am J Respir Crit Care Med. 2008 Jan 15;177(2):164-9. Epub 2007 Oct 25.
Abstract URL: Click here to view abstract

32. Sex, depression, and risk of hospitalization and mortality in chronic obstructive pulmonary disease.

Author: Fan VS; Ramsey SD; Giardino ND; Make BJ; Emery CF; Diaz PT; Benditt JO; Mosenifar Z; McKenna R Jr; Curtis JL; Fishman AP; Martinez FJ; Fan VS; Ramsey SD; Giardino ND; Make BJ; Emery CF; Diaz PT; Benditt JO; Mosenifar Z; McKenna R Jr; Curtis JL; Fishman AP; Martinez FJ; Fan VS; Ramsey SD; Giardino ND; Make BJ; Emery CF; Diaz PT; Benditt JO; Mosenifar Z; McKenna R Jr; Curtis JL; Fishman AP; Martinez FJ;
Institution: Health Services Research and Development Center of Excellence, Veterans Affairs Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108-1597, USA. vfan@u.washington.edu
Journal: Arch Intern Med. 2007 Nov 26;167(21):2345-53.
Abstract URL: Click here to view abstract

33. Effects of short-acting bronchodilators added to maintenance tiotropium therapy.

Author: Kerstjens HA; Bantje TA; Luursema PB; Sinninghe Damste HE; de Jong JW; Lee A; Wijker SP; Cornelissen PJ; Kerstjens HA; Bantje TA; Luursema PB; Sinninghe Damste HE; de Jong JW; Lee A; Wijker SP; Cornelissen PJ; Kerstjens HA; Bantje TA; Luursema PB; Sinninghe Damste HE; de Jong JW; Lee A; Wijker SP; Cornelissen PJ;
Institution: Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700 RB Groningen, the Netherlands. h.a.m.kerstjens@int.umcg.nl
Journal: Chest. 2007 Nov;132(5):1493-9. Epub 2007 Sep 21.
Abstract URL: Click here to view abstract

34. A randomized clinical trial of an activity and exercise adherence intervention in chronic pulmonary disease.

Author: Steele BG; Belza B; Cain KC; Coppersmith J; Lakshminarayan S; Howard J; Haselkorn JK; Steele BG; Belza B; Cain KC; Coppersmith J; Lakshminarayan S; Howard J; Haselkorn JK; Steele BG; Belza B; Cain KC; Coppersmith J; Lakshminarayan S; Howard J; Haselkorn JK;
Institution: Primary Care and Specialty Medicine Service, Department of Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA. bonnie.steele@med.va.gov
Journal: Arch Phys Med Rehabil. 2008 Mar;89(3):404-12.
Abstract URL: Click here to view abstract

35. Effects of a walking aid in COPD patients receiving oxygen therapy.

Author: Crisafulli E; Costi S; De Blasio F; Biscione G; Americi F; Penza S; Eutropio E; Pasqua F; Fabbri LM; Clini EM;
Institution: University of Modena-Reggio Emilia, Department of Pulmonary Rehabilitation, Ospedale Villa Pineta, Italy, Via Gaiato 127, 41026 Pavullo n/F (MO), USA.
Journal: Chest. 2007 Apr;131(4):1068-74.
Abstract URL: Click here to view abstract

36. Comparing COPD treatment: nebulizer, metered dose inhaler, and concomitant therapy.

Author: Tashkin DP; Klein GL; Colman SS; Zayed H; Schonfeld WH;
Institution: Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, Calif 90095-1690, USA. dtashkin@mednet.ucla.edu
Journal: Am J Med. 2007 May;120(5):435-41.
Abstract URL: Click here to view abstract