Wednesday, August 20, 2008 - 3:18AM EST

Clinical Trials

1. Ocular involvement in children with localised scleroderma: a multi-centre study.

Author
Zannin ME; Martini G; Athreya BH; Russo R; Higgins GC; Vittadello F; Alpigiani MG; Alessio M; Paradisi M; Woo P; Zulian F; Zannin ME; Martini G; Athreya BH; Russo R; Higgins G; Vittadello F; Alpigiani MG; Alessio M; Paradisi M; Woo P; Zulian F;
Institution
Department of Pediatrics, Via Giustiniani 3, 35128 Padova, Italy. ezannin@pediatria.unipd.it
Journal
Br J Ophthalmol. 2007 Oct;91(10):1311-4. Epub 2007 May 2.
Abstract URL
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2. The Pediatric Rheumatology European Society/American College of Rheumatology/European League against Rheumatism provisional classification criteria for juvenile systemic sclerosis.

Author
Zulian F; Woo P; Athreya BH; Laxer RM; Medsger TA Jr; Lehman TJ; Cerinic MM; Martini G; Ravelli A; Russo R; Cuttica R; de Oliveira SK; Denton CP; Cozzi F; Foeldvari I; Ruperto N;
Institution
Dipartimento di Pediatria, University of Padua, Padua, Italy. zulian@pediatria.unipd.it
Journal
Arthritis Rheum. 2007 Mar 15;57(2):203-12.
Abstract URL
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3. Recombinant human anti-transforming growth factor beta1 antibody therapy in systemic sclerosis: a multicenter, randomized, placebo-controlled phase I/II trial of CAT-192.

Author
Denton CP; Merkel PA; Furst DE; Khanna D; Emery P; Hsu VM; Silliman N; Streisand J; Powell J; Akesson A; Coppock J; Hoogen F; Herrick A; Mayes MD; Veale D; Haas J; Ledbetter S; Korn JH; Black CM; Seibold JR;
Institution
Royal Free Hospital, London, UK. c.denton@medsch.ucl.ac.uk
Journal
Arthritis Rheum. 2007 Jan;56(1):323-33.
Abstract URL
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4. High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study.

Author
Nash RA; McSweeney PA; Crofford LJ; Abidi M; Chen CS; Godwin JD; Gooley TA; Holmberg L; Henstorf G; LeMaistre CF; Mayes MD; McDonagh KT; McLaughlin B; Molitor JA; Nelson JL; Shulman H; Storb R; Viganego F; Wener MH; Seibold JR; Sullivan KM; Furst DE;
Institution
Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA. rnash@fhcrc.org
Journal
Blood. 2007 Aug 15;110(4):1388-96. Epub 2007 Apr 23.
Abstract URL
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5. Home parenteral nutrition--an effective and safe long-term therapy for systemic sclerosis-related intestinal failure.

Author
Brown M; Teubner A; Shaffer J; Herrick AL;
Institution
University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, Manchester, UK.
Journal
Rheumatology (Oxford). 2008 Feb;47(2):176-9. Epub 2007 Dec 14.
Abstract URL
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6. Mortality and risk factors of scleroderma renal crisis: a French retrospective study of 50 patients.

Author
Teixeira L; Mouthon L; Mahr A; Berezne A; Agard C; Mehrenberger M; Noel LH; Trolliet P; Frances C; Cabane J; Guillevin L;
Institution
Internal Medicine Department and Reference Center for Vasculitis and Systemic Sclerosis, Cochin Hospital, Assistance Publique-Hopitaux de Paris, and UPRES EA 4058, Paris-Descartes University, Faculty of Medicine, France.
Journal
Ann Rheum Dis. 2008 Jan;67(1):110-6. Epub 2007 Jun 8.
Abstract URL
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7. Long-term follow-up results after autologous haematopoietic stem cell transplantation for severe systemic sclerosis.

Author
Vonk MC; Marjanovic Z; van den Hoogen FH; Zohar S; Schattenberg AV; Fibbe WE; Larghero J; Gluckman E; Preijers FW; van Dijk AP; Bax JJ; Roblot P; van Riel PL; van Laar JM; Farge D;
Institution
Department of Rheumatology, Radboud University Nijmegen Medical Centre, P.O.Box 9101, 6500 HB Nijmegen, The Netherlands. M.Vonk@reuma.umcn.nl
Journal
Ann Rheum Dis. 2008 Jan;67(1):98-104. Epub 2007 May 25.
Abstract URL
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8. Systemic sclerosis in childhood: clinical and immunologic features of 153 patients in an international database.

Author
Martini G; Foeldvari I; Russo R; Cuttica R; Eberhard A; Ravelli A; Lehman TJ; de Oliveira SK; Susic G; Lyskina G; Nemcova D; Sundel R; Falcini F; Girschick H; Lotito AP; Buoncompagni A; Sztajnbok F; Al-Mayouf SM; Orban I; Ferri C; Athreya BH; Woo P; Zulian F;
Institution
University of Padua, Padua, Italy.
Journal
Arthritis Rheum. 2006 Dec;54(12):3971-8.
Abstract URL
Click here to view abstract

9. A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma.

Author
Hoyles RK; Ellis RW; Wellsbury J; Lees B; Newlands P; Goh NS; Roberts C; Desai S; Herrick AL; McHugh NJ; Foley NM; Pearson SB; Emery P; Veale DJ; Denton CP; Wells AU; Black CM; du Bois RM;
Institution
Royal Brompton Hospital, Imperial College, London, UK.
Journal
Arthritis Rheum. 2006 Dec;54(12):3962-70.
Abstract URL
Click here to view abstract

10. Cyclophosphamide versus placebo in scleroderma lung disease.

Author
Tashkin DP; Elashoff R; Clements PJ; Goldin J; Roth MD; Furst DE; Arriola E; Silver R; Strange C; Bolster M; Seibold JR; Riley DJ; Hsu VM; Varga J; Schraufnagel DE; Theodore A; Simms R; Wise R; Wigley F; White B; Steen V; Read C; Mayes M; Parsley E; Mubarak K; Connolly MK; Golden J; Olman M; Fessler B; Rothfield N; Metersky M; Tashkin DP; Elashoff R; Clements PJ; Goldin J; Roth MD; Furst DE; Arriola E; Silver R; Strange C; Bolster M; Seibold JR; Riley DJ; Hsu VM; Varga J; Schraufnagel DE; Theodore A; Simms R; Wise R; Wigley F; White B; Steen V; Read C; Mayes M; Parsley E; Mubarak K; Connolly MK; Golden J; Olman M; Fessler B; Rothfield N; Metersky M; Tashkin DP; Elashoff R; Clements PJ; Goldin J; Roth MD; Furst DE; Arriola E; Silver R; Strange C; Bolster M; Seibold JR; Riley DJ; Hsu VM; Varga J; Schraufnagel DE; Theodore A; Simms R; Wise R; Wigley F; White B; Steen V; Read C; Mayes M; Parsley E; Mubarak K; Connolly MK; Golden J; Olman M; Fessler B; Rothfield N; Metersky M;
Institution
University of California at Los Angeles, Los Angeles, USA. dtashkin@mednet.ucla.edu
Journal
N Engl J Med. 2006 Jun 22;354(25):2655-66.
Abstract URL
Click here to view abstract
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