Introduction to Sjogren's Syndrome
Dry Eyes in Sjogren's Syndrome
The primary function of tears is to bathe and cleanse the eye, keep it free from dust, and assist in lubrication so that it turns easily in its socket. Tears are produced by the lacrimal glands which are located above the outer corners of each eye. Blinking wipes away the tears by collecting it at the inner corner of the eye, where it is carried away via the tear ducts.
Tears are comprised of water as well as other components that protect the surface of the eyes. They contain many elements vital to the health of the eye surface such as epithelial growth factor (regulates cell growth and other functions), fibronectin (protein that supports cellular function), and vitamins. They also contain antimicrobial agents and nourishing substances that help in the mechanical and optical functioning of the eye.
Patients with Sjogren's syndrome who suffer from dry eye can develop severe ocular disorders in the absence of sufficient tears including dry, itchy, irritated and/or red eyes. Patients frequently report photophobia (aversion to light) and increased ocular irritation, especially at night.
Collectively, dry mouth and dry eyes are the two primary symptoms of Sjogren's syndrome and are known as the sicca (dry) syndrome.
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