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Obstructive Sleep Apnea Syndrome > What Your Doctor is Reading About Obstructive Sleep Apnea Syndrome > Clinical Trials

Clinical Trials

1. Effect of a 2 week CPAP treatment on mood states in patients with obstructive sleep apnea: a double-blind trial.

Author: Haensel A; Norman D; Natarajan L; Bardwell WA; Ancoli-Israel S; Dimsdale JE;
Institution: Department of General Internal Medicine, University Hospital Berne, Bern, Switzerland.
Journal: Sleep Breath. 2007 May 15;.
Abstract URL: Click here to view abstract

2. Percutaneous biphasic electrical stimulation for treatment of obstructive sleep apnea syndrome.

Author: Hu L; Xu X; Gong Y; Fan X; Wang L; Zhang J; Zeng Y;
Institution: Institute of Cor Pulmonale, Wenzhou Medical College, Wenzhou, Zhejiang 325027, China.
Journal: IEEE Trans Biomed Eng. 2008 Jan;55(1):181-7.
Abstract URL: Click here to view abstract

3. Palatal implants for the treatment of snoring and obstructive sleep apnea/hypopnea syndrome.

Author: Friedman M; Schalch P; Lin HC; Kakodkar KA; Joseph NJ; Mazloom N;
Institution: Department of Otolaryngology and Bronchoesophagology, Rush University Medical Center, Chicago, IL, USA. hednnek@aol.com <hednnek@aol.com>
Journal: Otolaryngol Head Neck Surg. 2008 Feb;138(2):209-16.
Abstract URL: Click here to view abstract

4. Auto-titrating continuous positive airway pressure therapy in patients with chronic heart failure and obstructive sleep apnoea: a randomized placebo-controlled trial.

Author: Smith LA; Vennelle M; Gardner RS; McDonagh TA; Denvir MA; Douglas NJ; Newby DE;
Institution: Cardiovascular Research, Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK.
Journal: Eur Heart J. 2007 May;28(10):1221-7. Epub 2007 Apr 30.
Abstract URL: Click here to view abstract

5. Outcome of adenotonsillectomy for obstructive sleep apnea in obese and normal-weight children.

Author: Mitchell RB; Kelly J;
Institution: Division of Pediatric Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, Saint Louis University School of Medicine, St Louis, MO 63104, USA. rmitch11@slu.edu
Journal: Otolaryngol Head Neck Surg. 2007 Jul;137(1):43-8.
Abstract URL: Click here to view abstract

6. A nasal cannula can be used to treat obstructive sleep apnea.

Author: McGinley BM; Patil SP; Kirkness JP; Smith PL; Schwartz AR; Schneider H;
Institution: Johns Hopkins Sleep Disorders Center, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21224, USA.
Journal: Am J Respir Crit Care Med. 2007 Jul 15;176(2):194-200. Epub 2007 Mar 15.
Abstract URL: Click here to view abstract

7. The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syndrome: evidence from a meta-analysis of placebo-controlled randomized trials.

Author: Haentjens P; Van Meerhaeghe A; Moscariello A; De Weerdt S; Poppe K; Dupont A; Velkeniers B;
Institution: Center for Outcomes Research and Laboratory for Experimental Surgery, Endocrinology, Pharmacology, and General Internal Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium. patrick.haentjens@uzbrussel.be
Journal: Arch Intern Med. 2007 Apr 23;167(8):757-64.
Abstract URL: Click here to view abstract

8. Effect of adjunctive modafinil on wakefulness and quality of life in patients with excessive sleepiness-associated obstructive sleep apnoea/hypopnoea syndrome : a 12-month, open-label extension study.

Author: Hirshkowitz M; Black J;
Institution: Michael E. DeBakey Veterans Affairs Medical Center - Sleep Diagnostic Clinic, Houston, Texas, USA.
Journal: CNS Drugs. 2007;21(5):407-16.
Abstract URL: Click here to view abstract

9. Sexual function and obstructive sleep apnea-hypopnea: a randomized clinical trial evaluating the effects of oral-appliance and continuous positive airway pressure therapy.

Author: Hoekema A; Stel AL; Stegenga B; van der Hoeven JH; Wijkstra PJ; van Driel MF; de Bont LG;
Institution: Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. a.hoekema@kchir.umcg.nl
Journal: J Sex Med. 2007 Jul;4(4 Pt 2):1153-62. Epub 2006 Nov 1.
Abstract URL: Click here to view abstract

10. Continuous positive airway pressure treatment of mild to moderate obstructive sleep apnea reduces cardiovascular risk.

Author: Buchner NJ; Sanner BM; Borgel J; Rump LC;
Institution: Department of Internal Medicine I, Marienhospital Herne, Ruhr University Bochum, Hoelkeskampring 40, D-44625 Herne, Germany. nikolaus.buechner@rub.de
Journal: Am J Respir Crit Care Med. 2007 Dec 15;176(12):1274-80. Epub 2007 Aug 2.
Abstract URL: Click here to view abstract

11. Objective evidence that bariatric surgery improves obesity-related obstructive sleep apnea.

Author: Haines KL; Nelson LG; Gonzalez R; Torrella T; Martin T; Kandil A; Dragotti R; Anderson WM; Gallagher SF; Murr MM;
Institution: Department of Surgery, Interdisciplinary Obesity Group, University of South Florida, Health Sciences Center, Tampa, FL 33601, USA.
Journal: Surgery. 2007 Mar;141(3):354-8. Epub 2006 Dec 8.
Abstract URL: Click here to view abstract

12. Diagnosis and initial management of obstructive sleep apnea without polysomnography: a randomized validation study.

Author: Mulgrew AT; Fox N; Ayas NT; Ryan CF;
Institution: University of British Columbia and Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.
Journal: Ann Intern Med. 2007 Feb 6;146(3):157-66.
Abstract URL: Click here to view abstract

13. A mandibular advancement device for the ENT office to treat obstructive sleep apnea.

Author: Maurer JT; Huber K; Verse T; Hormann K; Stuck B;
Institution: Sleep Disorders Center, Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital Mannheim, Mannheim, Germany. joachim.maurer@hno.ma.uni-heidelberg.de
Journal: Otolaryngol Head Neck Surg. 2007 Feb;136(2):231-5.
Abstract URL: Click here to view abstract

14. Efficacy of mirtazapine in obstructive sleep apnea syndrome.

Author: Carley DW; Olopade C; Ruigt GS; Radulovacki M;
Institution: Center for Narcolepsy, Sleep and Health Research, Department of Medical-Surgical Nursing, University of Illinois, M/C 719, Room 910, 40 South Wood Street, Chicago, IL 60612, USA. dwcarley@uic.edu
Journal: Sleep. 2007 Jan 1;30(1):35-41.
Abstract URL: Click here to view abstract

15. Effects of 2-week nocturnal oxygen supplementation and continuous positive airway pressure treatment on psychological symptoms in patients with obstructive sleep apnea: a randomized placebo-controlled study.

Author: Bardwell WA; Norman D; Ancoli-Israel S; Loredo JS; Lowery A; Lim W; Dimsdale JE;
Institution: Department of Psychiatry, Moores UCSD Cancer Center, University of California, San Diego, La Jolla, CA 92093-0804, USA. wabardwell@ucsd.edu
Journal: Behav Sleep Med. 2007;5(1):21-38.
Abstract URL: Click here to view abstract

16. Auto-adjusting versus fixed positive pressure therapy in mild to moderate obstructive sleep apnoea.

Author: Nolan GM; Doherty LS; Mc Nicholas WT;
Institution: Respiratory Sleep Disorders Unit, St. Vincent's University Hospital, Dublin, Ireland.
Journal: Sleep. 2007 Feb 1;30(2):189-94.
Abstract URL: Click here to view abstract

17. The effects of 1-year treatment with a herbst mandibular advancement splint on obstructive sleep apnea, oxidative stress, and endothelial function.

Author: Itzhaki S; Dorchin H; Clark G; Lavie L; Lavie P; Pillar G;
Institution: Sleep Laboratory, Rambam Medical Center, Haifa 31096, Israel.
Journal: Chest. 2007 Mar;131(3):740-9.
Abstract URL: Click here to view abstract

18. Adherence to and effectiveness of positive airway pressure therapy in children with obstructive sleep apnea.

Author: Marcus CL; Rosen G; Ward SL; Halbower AC; Sterni L; Lutz J; Stading PJ; Bolduc D; Gordon N;
Institution: Division of Pulmonary Medicine, Sleep Center, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. marcus@email.chop.edu
Journal: Pediatrics. 2006 Mar;117(3):e442-51.
Abstract URL: Click here to view abstract

19. Sleepiness and relationships in obstructive sleep apnea.

Author: Reishtein JL; Pack AI; Maislin G; Dinges DF; Bloxham TJ; George CF; Greenberg H; Kader GA; Mahowald MW; Younger JB; Weaver TE;
Institution: School of Nursing, and Division of Sleep Medicine and Center for Sleep and Respiratory Neurobiology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6096, USA.
Journal: Issues Ment Health Nurs. 2006 Apr;27(3):319-30.
Abstract URL: Click here to view abstract

20. Soft palate implants for the treatment of mild to moderate obstructive sleep apnea.

Author: Nordgard S; Stene BK; Skjostad KW;
Institution: Department of Otolaryngology-Head and Neck Surgery, St Olav University Hospital, Trondheim, Norway. stale.nordgard@medisin.ntnu.no
Journal: Otolaryngol Head Neck Surg. 2006 Apr;134(4):565-70.
Abstract URL: Click here to view abstract

21. Continuous positive airway pressure reduces nocturia in patients with obstructive sleep apnea.

Author: Margel D; Shochat T; Getzler O; Livne PM; Pillar G;
Institution: Institute of Urology, Rabin Medical Center, Petah Tiqva, Israel. sdmargel@bezeqint.net
Journal: Urology. 2006 May;67(5):974-7. Epub 2006 Apr 25.
Abstract URL: Click here to view abstract

22. Multilevel surgery for obstructive sleep apnea: short-term results.

Author: Verse T; Baisch A; Maurer JT; Stuck BA; Hormann K;
Institution: Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital Mannheim, Mannheim, Germany.
Journal: Otolaryngol Head Neck Surg. 2006 Apr;134(4):571-7.
Abstract URL: Click here to view abstract