Monday, December 1, 2008 - 9:58PM EST

Introduction to Erectile Dysfunction

Risk Factors for Erectile Dysfunction

A risk factor is anything that increases the chances of a person developing a disease or condition. Risk factors for erectile dysfunction (ED) include:

  • Advancing age - up to 50% of men age 50 experience ED and this number increases to 70% by age 70

  • Chronic diseases:

    • diabetes
    • heart disease
    • hypertension
    • high cholesterol/lipid levels in the bloodstream
    • chronic kidney failure
    • chronic liver disease
    • peripheral vascular disease
    • prostate disease
  • Endocrine (hormonal) disorders:

    • hypogonadism - inadequate function of the testes
    • thyroid disorders (hypothyroidism; hyperthyroidism)
    • hyperprolactinemia - excessive levels of prolactin in the blood
    • tumors of the pituitary gland
  • Nervous system disorders:

    • spinal cord injuries
    • multiple sclerosis
    • Parkinson's disease
    • Alzheimer's disease
    • stroke
  • Malformations or injuries of the penis:

    • Peyronie's disease - scarring of the shaft of the penis that can interfere with normal erections
    • priapism - a persistent, painful erection of the penis not associated with sexual arousal
    • curvarture of the penis acquired at birth
    • trauma to the penis
  • Medications:

    • antihypertensive medications (e.g., diuretics; Beta blockers)
    • antidepressant medications (e.g., selective serotonin reuptake inhibitors)
    • hormonal medications (e.g., antiandrogens)
    • some anticancer medications used for chemotherapy
    • H2-receptor blockers - a group of medications that are used to prevent the release of stomach acid and are used to treat heartburn and stomach ulcers
  • Psychological factors:

    • depression
    • sexual performance anxiety
    • interpersonal relationship problems
    • psyhological stress
  • Lifestyle factors:

    • smoking
    • obesity
    • alcohol abuse
    • lack of physical activity and exercise
  • Pelvic factors:

    • trauma to the pelvis
    • surgery and/or radiation therapy to the pelvic area